CAPN3 Polyclonal Antibody

• Background:

  Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

• Description:

  This is a CAPN3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Calcium-activated neutral proteinase 3, calpain 3, (p94), Calpain L3, Calpain large polypeptide L3 , Calpain p94, calpain p94, large [catalytic] subunit, calpain, large polypeptide L3, Calpain-3, CAN3, CANP 3, CANP3, CANPL3, CAPN3, LGMD 2A, LGMD2, LGMD2A, Lp82, Lp85, MGC10

• Swiss Prot:

  P20807

• Accession Number:

  BC003521

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human CAPN3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.4 mg/mL

• Dilution:

  IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG