PE/Cyanine5 Anti-Human CD20 Antibody

• Background:

  CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

• Synonyms:

  Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1

• Gene ID:

  931

• Swiss Prot:

  P11836

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Conjugation:

  PE/Cyanine5

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4