Purified Anti-Mouse CD366/Tim-3 Antibody

• Background:

  CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells) . Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

• Description:

  This is a Purified Anti-Mouse CD366/Tim-3 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TIM3, TIMD3, HAVcr-2, TIMD-3

• Gene ID:

  84868

• Swiss Prot:

  Q8VIM0

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300

• Storage Conditions:

  Store at 2~8°C. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG2a, κ