PE/Cyanine7 Anti-Human CD39 Antibody

• Background:

  Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details

• Synonyms:

  SPG64,NTPDase1,ATPDase,CD 39

• Gene ID:

  953

• Swiss Prot:

  P49961

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Conjugation:

  PE/Cyanine7

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4