PE/Cyanine5 Anti-Human CD27 Antibody

• Background:

  CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.

• Synonyms:

  CD27L receptor,T-cell activation antigen CD27,T14,S152,TNFRSF7

• Gene ID:

  939

• Swiss Prot:

  P26842

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Conjugation:

  PE/Cyanine5

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4