Biotin Anti-Human CD62L Antibody

• Background:

  CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

• Description:

  This is a Biotin Anti-Human CD62L Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22

• Gene ID:

  6402

• Swiss Prot:

  P14151

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  Biotin

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C. Do not freeze.

• Host or Source:

  Mouse

• Isotype:

  Mouse IgG1, κ