Biotin Anti-Mouse CD40 Antibody

• Background:

  CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

• Description:

  This is a Biotin Anti-Mouse CD40 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5

• Gene ID:

  21939

• Swiss Prot:

  P27512

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  Biotin

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG2a, κ