Purified Anti-Mouse CD86 Antibody

• Background:

  CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4) . CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

• Description:

  This is a Purified Anti-Mouse CD86 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1

• Gene ID:

  12524

• Swiss Prot:

  P42082

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300

• Storage Conditions:

  Store at 2~8°C. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG2a, κ