Anti-Synaptogyrin 3/SYNGR3 Antibody Picoband®, APC Conjugate

Anti-Synaptogyrin 3/SYNGR3 Antibody Picoband®, APC Conjugate

• Background: Synaptogyrin 3 is a protein that in humans is encoded by the SYNGR3 gene. This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family.
• Description: Boster Bio Anti-Synaptogyrin 3/SYNGR3 Antibody Picoband® catalog # A14692-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
• Synonyms: Transmembrane protein 199; TMEM199; C17orf32
• Gene Name: transmembrane protein 199
• Gene ID: 9143
• UniProt: O43761
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Cross Reactivity: No cross-reactivity with other proteins.
• Immunogen: E.coli-derived human Synaptogyrin 3/SYNGR3 recombinant protein (Position: N45-Y229).
• Clonality: Polyclonal
• Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
• Applications: WB,IHC,ELISA
• Purification: Immunogen affinity purified.
• Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Form: Lyophilized
• Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Function: Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis.
• Components: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
• References & Citations: 1. Kedra, D., Pan, H.-Q., Seroussi, E., Fransson, I., Guilbaud, C., Collins, J. E., Dunham, I., Blennow, E., Roe, B. A., Piehl, F., Dumanski, J. P. Characterization of the human synaptogyrin gene family. Hum. Genet. 103: 131-141, 1998.
• Storage Conditions: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.
• Calculated Molecular Weight: 64099 MW
• Observed Molecular Weight: 24 kDa
• Fragment: Rabbit IgG
• Applications Notes: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
  Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat
  ELISA, 0.1-0.5 μg/ml, -
  
• Subcellular Location: Endoplasmic reticulum membrane. Multi-pass membrane protein. COPI-coated vesicle membrane. Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Multi-pass membrane protein.
• Protein Name: DAP3 binding cell death enhancer 1