Anti-CBS Antibody (Center)

• Background:

  CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

• Description:

  Boster Bio Anti-CBS Antibody (Center) (Catalog # A00130-2) . Tested in WB, IHC-P-Leica, Flow Cytometry, IF application (s) . This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, CBS

• Gene Name:

  CBS

• UniProt:

  P35520

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the Central region of human CBS.

• Clonality:

  Polyclonal

• Tissue Specificity:

  In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney

• Applications:

  WB, IHC-P-Leica, Flow Cytometry, IF

• Field of Research:

  Cancer, Metabolism, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  239817742050632523974653

• Molecular Weight:

  60587 Da

• Shipping Conditions:

  Available

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Subcellular Location:

  Cytoplasm. Nucleus

• Prediction Reactivity:

  Monkey