Anti-GDF11 Antibody (N-term)

• Background:

  GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

• Description:

  Boster Bio Anti-GDF11 Antibody (N-term) (Catalog # A02355) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Mouse.

• Synonyms:

  Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11

• Gene Name:

  GDF11

• UniProt:

  O95390

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.

• Clonality:

  Polyclonal

• Tissue Specificity:

  In the embryo, strong expression is seen in the palatal epithelia, including the medial edge epithelial and midline epithelial seam of the palatal shelves. Less pronounced expression is also seen throughout the palatal shelf and tongue mesenchyme

• Applications:

  IHC-P, WB

• Field of Research:

  Cell Biology, Neuroscience, Signal Transduction, Cytokines

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  3121511528257634

• Molecular Weight:

  45091 Da

• Shipping Conditions:

  Available

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Subcellular Location:

  Secreted.