Recombinant SARS-CoV-2 ORF7a protein

• Background:

  Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 thereby interfering with its glycosylation. May suppress small interfering RNA (siRNA) . May bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes.

• Synonyms:

  7a; Accessory protein 7a; Protein U122; Protein X4

• UniProt:

  P0DTC7

• Accession Number:

  YP_009724395.1

• Expression System:

  E. coli

• Tag:

  N-His

• Sequence:

  Glu16-Tyr97

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 90 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  12.1 kDa

• Formulation:

  Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
  Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
  Please refer to the specific buffer information in the printed manual.

• Species:

  SARS-CoV-2