Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)

Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)

• Background: Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60% and 67% aa identity with mouse and bovine CXCL6, respectively.
• Abbreviation: C-X-C Motif Chemokine 6;CXCL6
• Synonyms: C-X-C Motif Chemokine 6, CKA-3, CXCL6, Chemokine Alpha 3, GCP-2, GCP2, Granulocyte Chemotactic Protein 2, SCYB6, Small-Inducible Cytokine B6
• CAS Number: 9000-83-3
• UniProt: P80162
• Accession Number: P80162
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-His
• Sequence: Gly38-Asn114
• Field of Research: immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 13 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.