Recombinant Human Semaphorin 4D/SEMA4D Protein (Fc Tag)
CAT:
763-PKSH033023-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human Semaphorin 4D/SEMA4D Protein (Fc Tag)
- Background: Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
- Abbreviation: SEMA4D;CD100
- Synonyms: A8, BB18, C9orf164, CD100, GR3, M-sema-G, SEMAJ, Semaphorin-4D, coll-4
- CAS Number: 9000-83-3
- UniProt: Q92854
- Accession Number: AAH54500.1
- Host: HEK293 Cells
- Origin Species: Human
- Tag: C-Fc
- Sequence: Met22-Arg734
- Field of Research: Neuroscience;immunology
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 130-170 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.