PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]

• Background:

  CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

• Abbreviation:

  CD183

• Gene ID:

  12766

• UniProt:

  O88410

• Host:

  Armenian Hamster

• Reactivity:

  Mouse

• Target:

  C-X-C chemokine receptor type 3; CD183/CXCR3; CXC-R3; CXCR-3; Cxcr3; IP-10 receptor; Interferon-inducible protein 10 receptor

• Clonality:

  Monoclonal

• Clone:

  CXCR3-173

• Conjugation:

  PE/Cyanine 5.5

• Applications:

  FCM

• Field of Research:

  Immunology; Innate Immunity

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Armenian Hamster IgG