PerCP/Cyanine5.5 Anti-Human CD20 Antibody[BCA/B20]

• Background:

  CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn) . It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

• Abbreviation:

  CD20

• Gene ID:

  931

• UniProt:

  P11836

• Host:

  Mouse

• Reactivity:

  Human

• Target:

  B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; CD20; Leukocyte surface antigen Leu-16; MS4A1; Membrane-spanning 4-domains subfamily A member 1

• Clonality:

  Monoclonal

• Clone:

  BCA/B20

• Conjugation:

  PerCP/Cyanine 5.5

• Applications:

  FCM

• Field of Research:

  Costimulatory Molecules; Immunology

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Mouse IgG2a, κ