Human C-C Motif Chemokine 5, CCL5 Primacu™ ELISA Kit

Human C-C Motif Chemokine 5, CCL5 Primacu™ ELISA Kit

• Background: Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 5(CCL5) is chemotactic for T cells, basophils and eosinophils. Chemokin ligand 5(CCL5) has been considered a HIV-supressor secreted by CD8+ T cells and other immune cells. Chemokin ligand 5(CCL5) is a key to activating recruit leukocytes into inflammatory sites and in the presence of particular cytokines released by T cells, it can change the NK cells into CHAK cells. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
• Description: C-C motif chemokine 5
• Synonyms: D17S136E;SCYA5
• Gene Name: CCL5
• Gene ID: 6352
• UniProt: P13501
• Origin Species: Human
• Reactivity: Human
• Target: CCL5
• Field of Research: Neuroscience,Cardiovascular,Immunology,Stem cells
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 0.5 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 0.78-50 pg/mL
• Sensitivity: 0.32 pg/mL
• Weight: 9990
• Storage Temperature: 2-8°C