Mouse Tumor Necrosis Factor, Tnf Primacu™ ELISA Kit

Mouse Tumor Necrosis Factor, Tnf Primacu™ ELISA Kit

• Background: Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & Antibody Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
• Description: Tumor necrosis factor
• Synonyms: Tnfa;Tnfsf2
• Gene Name: Tnf
• Gene ID: 21926
• UniProt: P06804
• Origin Species: Mouse
• Reactivity: Mouse
• Target: TNF-alpha
• Field of Research: Cancer,Cardiovascular,Immunology,Metabolism,Microbiology,Neuroscience,Signal transduction
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 60 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 93.75-6000 pg/mL
• Sensitivity: 43 pg/mL
• Weight: 25896
• Storage Temperature: 2-8°C