Cephalin form bovine brain

• Description :

  Cephalin form bovine brain is an orally active phospholipid widely present in organisms.Cephalin form bovine brain participates in the formation of autophagosome membrane as a lipid anchor of autophagy-related protein Atg8/LC3. Cephalin form bovine brain enhances Autophagic flux, promotes cell differentiation, regulates lipid droplet fusion, delays aging, and also affects lipid metabolism and membrane integrity[1][2][3][4][5][6][7].

• UNSPSC :

  12352200

• Hazard Statement :

  H301-H311-H331

• Target :

  Autophagy; Liposome

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Autophagy; Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/phosphatidylethanolamine.html

• Purity :

  98.0

• Solubility :

  DMSO : 5 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)

• Smiles :

  [Cephalinformbovinebrain]

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

• References & Citations :

  [1]Rockenfeller P, et al. Phosphatidylethanolamine positively regulates autophagy and longevity. Cell Death Differ. 2015 Mar;22 (3) :499-508. |[2]Ishigamori H, et al. Docosahexaenoic acid-containing phosphatidylethanolamine enhances HL-60 cell differentiation by regulation of c-jun and c-myc expression. Mol Cell Biochem. 2005 Jul;275 (1-2) :127-33. |[3]Cohen BC, et al. Lipid Droplet Fusion in Mammary Epithelial Cells is Regulated by Phosphatidylethanolamine Metabolism. J Mammary Gland Biol Neoplasia. 2017 Dec;22 (4) :235-249.|[4]Wellner N, et al. Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice. Biochim Biophys Acta. 2011 Sep;1811 (9) :508-12.|[5]Li Z, et al. The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab. 2006 May;3 (5) :321-31. |[6]Imaizumi K, et al. The contrasting effect of dietary phosphatidylethanolamine and phosphatidylcholine on serum lipoproteins and liver lipids in rats. J Nutr. 1983 Dec;113 (12) :2403-11.|[7]Imaizumi K, et al. Effect of phosphatidylethanolamine and its constituent base on the metabolism of linoleic acid in rat liver. Biochim Biophys Acta. 1989 Oct 17;1005 (3) :253-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [90989-93-8]