EGR1 Recombinant Protein

• Gene Name:

  Early growth response 1

• Gene Aliases:

  A530045N19Rik; early growth response protein 1; egr; Egr-; Egr-1; ETR10; ETR103; Krox; Krox-; Krox-1; Krox24; Krox-24; Krox-24 nuclear protein; nerve growth factor-induced protein A; NG; NGF; NGF1; NGF1-A; NGFIA; NGFI-A; TI; TIS8; transcription factor Zif268; Zen; Zenk; Zfp-; Zfp-6; Zif26; Zif268; zinc finger protein Krox-24.

• Gene ID:

  13653

• Accession Number:

  NP_031939.1

• Reactivity:

  Mouse|Mus musculus

• Target:

  Transcriptional regulator (PubMed:8336701, PubMed:8703054, PubMed:15958557) . Recognizes and binds to the DNA sequence 5'-GCG (T/G) GGGCG-3' (EGR-site) in the promoter region of target genes (PubMed:8703054, PubMed:15958557, PubMed:2028256, PubMed:8939742) . Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity) . Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia (PubMed:11100120, PubMed:15958557) . Plays a role in the regulation of cell survival, proliferation and cell death (PubMed:15265859, PubMed:15958557) . Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation (PubMed:15958557) . Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy (PubMed:15265859) . Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia (PubMed:11100120) . Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (PubMed:8703054) .

• Conjugation:

  Unconjugated

• Type:

  Protein

• Source:

  E.coli

• Applications:

  Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 ug/mL (prior to lyoph)

• Format:

  Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

• Reconstitution:

  2°C to 8°C|-80°C

• Molecular Weight:

  22/27kDa

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  Egr1

• Host or Source:

  E.coli

• Protein Name:

  Early growth response protein 1

• Gene Name URL:

  Egr1

• CAS Number:

  9000-83-3

• Nucleotide Accession Number:

  NM_007913.5