CRIP2 Antibody

• Gene Name:

  Epithelial splicing regulatory protein 1

• Gene Aliases:

  2210008M09Rik; A630065D16; BC031468; epithelial splicing regulatory protein 1; Rbm3; Rbm35a; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A.

• Gene ID:

  207920

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_918944.2

• Reactivity:

  Mouse

• Immunogen:

  Anti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein.

• Target:

  MRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT) . Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity) .

• Clonality:

  Monoclonal

• Clone:

  27H12.F3.H5

• Conjugation:

  Unconjugated

• Type:

  Monoclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Mouse

• Format:

  Liquid (sterile filtered)

• Reconstitution:

  -20°C|See manual

• NCBI Gene Symbol:

  Esrp1

• Host or Source:

  Mouse

• Protein Name:

  Epithelial splicing regulatory protein 1|epithelial splicing regulatory protein 1 isoform 1 [Mus musculus]

• Gene Name URL:

  Esrp1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001270837.1NM_001270841.1NM_001312.3