Lipoxin A4 methyl ester

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 ?M.[2] LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2], [3], [4]

• Smiles:

  CCCCC[C@H](O)\C=C\C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC

• Molecular Formula:

  C21H34O5

• Molecular Weight:

  366.498

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  97643-35-1