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GNF-7

CAT: 0026-B1139-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B1139-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNF-7 is a multi-targeted kinase inhibitor that inhibits activated CDC42 kinase 1 (ACK1) and germinal center kinase (GCK) inducing cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. It also displays significant in vivo efficacy against T315l-Bcr-Abl without notable toxicity in a bioluminescent xenograft mouse model using transformed T315l-Bcr-Abl-Ba/F3 cell line that has a stable luciferase expression.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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