STAT3, phosphorylated (Tyr705) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF) (FITC) Antibody

• Catalog number
  GEN632677
• Price
  Please ask
• Size
  50ug

• Also known as
  STAT3
• Other names
  signal transducer and activator of transcription 3 isoform 1; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor; signal transducer and activator of transcription 3 (acute-phase response factor); Acute-phase response factor
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  STAT3; STAT3; APRF; HIES; APRF
• Gene name synonims
  STAT3; STAT3; APRF; HIES; APRF
• Other gene names
  STAT3; STAT3; APRF; HIES; APRF
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  6D76
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Canine, Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at -20 degrees Celsius.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  STAT3   phosphorylated   Tyr705   Signal   Transducer   Activator   Transcription   Acute-phase   Response   Factor   APRF  
• Gene symbol
  STAT3
• Short name
  STAT3, phosphorylated (Tyr705) (Signal Transducer Activator of Transcription 3, Acute-phase Response Factor, APRF) (FITC) Antibody
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, Fluorescein
• Label
  FITC
• Alternative name
  Anti-STAT3, phosphorylated (Tyr705) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF) (FITC)
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541

Gene info

• Identity
  HGNC:11364
• Gene
  STAT3
• Long gene name
  signal transducer and activator of transcription 3
• Synonyms gene name
  • signal transducer and activator of transcription 3 (acute-phase response factor)
• Synonyms
  • APRF
• GenBank acession
  • BC014482
• Locus
  17q21.2
• Discovery year
  1995-11-08
• Entrez gene record
  6774
• Pubmed identfication
  • 7512451
• RefSeq identity
  • NM_139276
  • NM_003150
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150645
• Locus Specific Databases
  • STAT3base: Mutation registry for Hyper-IgE syndrome
  • LRG_112

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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