STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Cell Adaptor Protein 1)

• Catalog number
  MBS619851
• Price
  Please ask
• Size
  100ug

• Alternative name1
  Anti-STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Cell Adaptor Protein 1)
• Alternative name2
  STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Cell Adaptor Protein 1)
• Alternative name3
  STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Cell Adaptor Protein 1)
• Alternative name4
  STAP1
• Alternative name5
  Anti -STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Cell Adaptor Protein 1)
• Other names
  signal-transducing adaptor protein 1; Signal-transducing adaptor protein 1; signal-transducing adaptor protein 1; OTTHUMP00000159639; OTTHUMP00000159640; docking protein BRDG1; BCR downstream signaling 1; stem cell adaptor protein 1; BCR downstream-signaling protein 1; signal-transducing adaptor protein-1; signal transducing adaptor family member 1; BCR downstream-signaling protein 1; Docking protein BRDG1; Stem cell adaptor protein 1
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  STAP1; STAP1; BRDG1; STAP-1; BRDG1
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  IgG
• Clone
  Polyclonal antibody
• Host organism
  Host: Goat; Source: Human
• Species reactivity
  Human
• Specificity and cross reactivity
  Recognizes human BRDG1.
• Purification method
  Purified
• Form Appearance
  Supplied as a liquid in Tris-saline, 0.02% sodium azide, 0.5% BSA.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested for
  Western Blot (WB)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  For cells, cell lines and tissues in culture till half confluency. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
• Test
  Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.

• Gene target
  STAP1   Signal   Transducing   Adaptor   Protein   STAP   STAP-1   BCR   Downstream   Signaling   Protein   BRDG1   Docking   Protein   BRDG1   Signal   Transducing   Adaptor   Family   Member   Stem   Adaptor   Protein  
• Gene symbol
  STAP1, CYGB, UXT, STAP2, BCRP1, BCRP2, BCRP4, BCR, IGHVII-1-1, MIR1-1
• Short name
  STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor Family Member 1, Stem Adaptor Protein 1)
• Alternative name
  STAP1 (Signal Transducing Adaptor Protein 1, STAP 1, STAP-1, BCR Downstream Signaling Protein 1, BRDG1, Docking Protein BRDG1, Signal Transducing Adaptor family Member 1, progenitor cellular Adaptor Protein 1)
• Tissue
  cell, stem

Gene info

• Identity
  HGNC:24133
• Gene
  STAP1
• Long gene name
  signal transducing adaptor family member 1
• Synonyms
  • STAP-1
  • BRDG1
• Synonyms name
  • BCR downstream signaling 1
• GenBank acession
  • AB023483
• Locus
  4q13.2
• Discovery year
  2007-08-09
• Entrez gene record
  26228
• Pubmed identfication
  • 10518561
  • 10679268
• RefSeq identity
  • NM_012108
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000129304

Gene info

• Identity
  HGNC:16505
• Gene
  CYGB
• Long gene name
  cytoglobin
• Synonyms
  • HGB
  • STAP
• Synonyms name
  • stellate cell activation-associated protein
  • histoglobin
• GenBank acession
  • AJ315162
• Locus
  17q25.1
• Discovery year
  2001-09-21
• Entrez gene record
  114757
• Pubmed identfication
  • 11919282
• RefSeq identity
  • NM_134268
• VEGA ID
  OTTHUMG00000180289

Gene info

• Identity
  HGNC:12641
• Gene
  UXT
• Long gene name
  ubiquitously expressed prefoldin like chaperone
• Synonyms gene name
  • ubiquitously-expressed transcript
  • ubiquitously-expressed, prefoldin-like chaperone
• Synonyms
  • ART-27
  • STAP1
• Synonyms name
  • androgen receptor trapped clone 27
  • SKP2-associated alpha PFD 1
• GenBank acession
  • AF092737
• Locus
  Xp11.23
• Discovery year
  1998-09-03
• Entrez gene record
  8409
• Pubmed identfication
  • 10087202
  • 16221885
• RefSeq identity
  • NM_153477
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000021453

Gene info

• Identity
  HGNC:30430
• Gene
  STAP2
• Long gene name
  signal transducing adaptor family member 2
• Synonyms
  • STAP-2
  • BKS
• GenBank acession
  • AJ245719
• Locus
  19p13.3
• Discovery year
  2007-08-09
• Entrez gene record
  55620
• Pubmed identfication
  • 10980601
  • 11441184
• RefSeq identity
  • NM_001013841
• VEGA ID
  OTTHUMG00000181884

Gene info

• Identity
  HGNC:39073
• Gene
  BCRP1
• Long gene name
  BCR pseudogene 1
• Synonyms gene name
  • breakpoint cluster region pseudogene 1
• Synonyms
  • BCR-1
• Locus
  22q11.23
• Discovery year
  2010-09-30
• Entrez gene record
  644079
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_009423
• VEGA ID
  OTTHUMG00000150768

Gene info

• Identity
  HGNC:1015
• Gene
  BCRP2
• Long gene name
  BCR pseudogene 2
• Synonyms gene
  • BCR2
  • BCRL2
• Synonyms gene name
  • breakpoint cluster region-like 2
  • breakpoint cluster region pseudogene 2
• Synonyms
  • BCR-2
• Locus
  22q11.21
• Discovery year
  2001-06-22
• Entrez gene record
  400892
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_007131
• VEGA ID
  OTTHUMG00000150627

Gene info

• Identity
  HGNC:1017
• Gene
  BCRP4
• Long gene name
  BCR pseudogene 4
• Synonyms gene
  • BCR4
  • BCRL4
• Synonyms gene name
  • breakpoint cluster region-like 4
  • breakpoint cluster region pseudogene 4
• Synonyms
  • BCR-4
• GenBank acession
  • D87002
• Locus
  22q11.22
• Discovery year
  2001-06-22
• Entrez gene record
  616
• Pubmed identfication
  • 9074928
• RefSeq identity
  • NG_000002
• VEGA ID
  OTTHUMG00000151175

Gene info

• Identity
  HGNC:1014
• Gene
  BCR
• Long gene name
  BCR activator of RhoGEF and GTPase
• Synonyms gene
  • D22S11
  • BCR1
• Synonyms gene name
  • breakpoint cluster region
  • BCR, RhoGEF and GTPase activating protein
• Synonyms
  • D22S662
  • CML
  • PHL
  • ALL
• Locus
  22q11.23
• Discovery year
  1986-01-01
• Entrez gene record
  613
• Pubmed identfication
  • 1657398
  • 18070886
• RefSeq identity
  • NM_004327
• Classification
  • C2 domain containing
  • My-T-BRC complex
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000150655
• Locus Specific Databases
  • LRG_1112

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

MeSH Data

• Name
  Gene Knockdown Techniques
• Concept
  Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
• Tree numbers
  • E05.393.335.500
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

Similar products