Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1)

  • Catalog number
  • Price
    Please ask
  • Size
    50 μg
  • Category
    Primary Antibodies
  • Long description
    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
  • Antibody come from
    N-terminal region of human
  • Other description
    Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
  • Clone
  • Antigen antibody binding interaction
    Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1) Antibody
  • Antibody is raised in
  • Antibody s reacts with
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
  • Antibody s suited for
    Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (6 µg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Storage
    Long term: -70ºC; Short term: +4ºC
  • Relevant references
    no information yet
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
  • About
    Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • Gene target
  • Gene symbol
  • Short name
    Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1)
  • Technique
    Enzyme, Rabbit, anti, antibody to, enzymes
  • Host
    Rabbit, Rabbits
  • Isotype
    not specified
  • Label
  • Alternative name
    production species: rabbit antibody to b-site amyloid beta (A4) precursor protein-Cleaving Enzyme 1 (BACE1)
  • Alternative technique
    enzymes, rabbit-anti, antibodies
  • Alternative to gene target
    amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
Gene info
  • Identity
  • Gene
  • Long gene name
    APP divergent transcript
  • Locus
  • Discovery year
  • Classification
    • Divergent transcripts
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    beta-secretase 1
  • Synonyms gene
  • Synonyms gene name
    • beta-site APP-cleaving enzyme
    • beta-site APP-cleaving enzyme 1
  • GenBank acession
  • Locus
  • Discovery year
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Peptidase family A1
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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