TRAF4, CT (TRAF4, CART1, MLN62, RNF83, TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, RING finger protein 83)
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Catalog number
MBS6005907
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Price
Please ask
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Size
0,2 mL
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Other size
please contact us to order other different size
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Gene
Cys or cysteines ChEMBL54943, Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
TRAF4, TNF, ALX1, TNFRSF1A, TNFRSF1B, LTBR
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Short name
TRAF4, CT (TRAF4, CART1, MLN62, RNF83, TNF receptor-associated factor 4, Cysteine-rich domain associated with RING Traf domains protein 1, Metastatic lymph node 62 protein, RING finger protein 83)
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Alternative name
tumor necrosis factor receptor-associated factor 4, CT (tumor necrosis factor receptor-associated factor 4, CART1, MLN62, RNF83, tumor necrosis factor receptor-associated factor 4, Cysteine-rich domain associated including RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, RING finger protein 83)
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Alternative to gene target
TNF receptor-associated factor 4, CART1 and MLN62 and RNF83, TRAF4 and IDBG-37645 and ENSG00000076604 and 9618, WW domain binding, nuclei, Traf4 and IDBG-202221 and ENSMUSG00000017386 and 22032, LOC783305 and IDBG-632122 and ENSBTAG00000038990 and 781568,783305
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Tissue
lymph, node
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Gene info
Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
ALX homeobox 1
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Synonyms gene
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Synonyms gene name
- cartilage paired-class homeoprotein 1
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GenBank acession
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Locus
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Discovery year
1999-08-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PRD class homeoboxes and pseudogenes
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VEGA ID
Gene info
Gene info
Gene info
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