RUNX2, phosphorylated (Ser465) (Runt-related Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, [RUNX2]
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Catalog numberMBS630580
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Price5.5 USD
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SizeNA
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Products_typeAntibody
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ReactivityHuman
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DescriptionThe RUNX2, phosphorylated (Ser465) (Runt- Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, [RUNX2] is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbolRUNX2-AS1, RUNX2, NFYC, NFYB, NFYA, MIR1302-3, MIR509-3, MIR7-3
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Short nameRUNX2, phosphorylated (Ser465) (Runt- Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, [RUNX2]
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HostRabbit
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Alternative nameRUNX2, phosphorylated (Ser465) (Runt-related Transcription Factor 2, Core-binding Factor functionnal sequence a-1, CBF-a-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 a A functionnal sequence, PEBP2-a A, PEA2-a A, [RUNX2]
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Virusleukemia
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Gene info
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Identity
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Gene
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Long gene nameRUNX2 antisense RNA 1
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Locus
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Discovery year2017-05-12
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameRUNX family transcription factor 2
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Synonyms gene
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Synonyms gene name
- runt-related transcription factor 2
- runt related transcription factor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Runt-related transcription factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit gamma
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Synonyms gene name
- nuclear transcription factor Y, gamma
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit beta
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Synonyms gene name
- nuclear transcription factor Y, beta
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Synonyms
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Locus
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Discovery year1991-11-08
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit alpha
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Synonyms gene name
- nuclear transcription factor Y, alpha
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Synonyms
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Locus
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Discovery year1991-11-08
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
MeSH Data
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Name
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ConceptScope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
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Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery