Recombinant Human Fc Fragment Of IgM Receptor

• Catalog number
  MBS141365
• Price
  Please ask
• Size
  5x0.01 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Fc Fragment Of IgM Receptor]
• Products_name_syn
  [Fc Fragment Of IgM Receptor Human Recombinant; Fas apoptotic inhibitory molecule 3; IgM Fc fragment receptor; Regulator of Fas-induced apoptosis Toso; FAIM3; TOSO; FCMR Human]
• Other_names
  [Fas apoptotic inhibitory molecule 3; Fas apoptotic inhibitory molecule 3; fas apoptotic inhibitory molecule 3; Fc fragment of IgM receptor; Regulator of Fas-induced apoptosis Toso]
• Products_gene_name
  [FCMR]
• Other_gene_names
  [FCMR; FAIM3; TOSO; FAIM3; TOSO]
• Purity
  >95.0% as determined by SDS-PAGE
• Form
  Filtered White Lyophilized (Freeze-Dried) PowderFiltered (0.4 um) and lyophilized from 0.5mg/ml in 50mM acetate buffer, pH 4.
• Storage_stability
  Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Receptor  
• Gene symbol
  FCAR, FCGR1BP, FCGR1A
• Short name
  Recombinant Fc Of IgM Receptor
• Technique
  Recombinant, IgM, FC, IgMs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Isotype
  IgM, Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common. IgM
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens fragment c Fragment on Immunoglobulin M Receptor
• Alternative technique
  rec, immunoglobulin-m

Gene info

• Identity
  HGNC:3608
• Gene
  FCAR
• Long gene name
  Fc fragment of IgA receptor
• Synonyms gene name
  • Fc fragment of IgA, receptor for
• Synonyms
  • CD89
• GenBank acession
  • X54150
• Locus
  19q13.42
• Discovery year
  1991-06-06
• Entrez gene record
  2204
• Pubmed identfication
  • 1577457
• RefSeq identity
  • NM_002000
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000065936

Gene info

• Identity
  HGNC:3614
• Gene
  FCGR1BP
• Long gene name
  Fc gamma receptor Ib, pseudogene
• Synonyms gene
  • FCGR1B
• Synonyms gene name
  • Fc fragment of IgG, high affinity Ib, receptor for (CD64)
  • Fc fragment of IgG, high affinity Ib, receptor (CD64)
  • Fc fragment of IgG receptor Ib
• Synonyms
  • CD64b
• Locus
  1p11.2
• Discovery year
  1992-12-03
• Entrez gene record
  2210
• Pubmed identfication
  • 8697799
  • 9763663
• RefSeq identity
  • NM_001017986
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000040903

Gene info

• Identity
  HGNC:3613
• Gene
  FCGR1A
• Long gene name
  Fc gamma receptor Ia
• Synonyms gene name
  • Fc fragment of IgG, high affinity Ia, receptor for (CD64)
  • Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Fc fragment of IgG receptor Ia
• Synonyms
  • CD64
  • CD64A
  • FcgammaRI
  • FcgammaRIa
  • FCG1
  • FCGR1
• Synonyms name
  • Fc gamma RI
• GenBank acession
  • BC032634
• Locus
  1q21.2
• Discovery year
  1992-12-03
• Entrez gene record
  2209
• Pubmed identfication
  • 8697799
  • 9763663
• RefSeq identity
  • NM_000566
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000012089
• Locus Specific Databases
  • FCGR1Abase: Mutation registry for CD64 deficiency
  • LRG_59

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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