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Products_type
Antibody
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Products_short_name
[IL10]
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Products_name_syn
[Anti-IL10 Antibody (clone JES5-2A5) IHC-plus; IL10; CSIF; GVHDS; IL-10; IL10A; Interleukin-10; Interleukin 10; TGIF; Mouse IL10]
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Other_names
[interleukin-10; Interleukin-10; interleukin-10; T-cell growth inhibitory factor; cytokine synthesis inhibitory factor; interleukin 10; Cytokine synthesis inhibitory factor; CSIF]
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Products_gene_name
[IL10]
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Other_gene_names
[IL10; IL10; CSIF; TGIF; GVHDS; IL-10; IL10A; IL-10; CSIF]
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Clonality
Monoclonal
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Clone
[JES5-2A5]
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Reactivity
Mouse
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Specificity
A recognizes mouse Cytokine synthesis inhibitory factor(CSIF), also known, as interleukin IL-10). IL-10 is produces by Ly-1 (CD-5) expressing B cells and a subset of stimulated T cells. IL-10 has a wide range of biological properties, including the inhibition of macrophage and T helper cell mediated cytokine synthesis and the suspension of the delayed hypersensitivity response. Is reported to neutralize the activity of murine IL-10.
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Purity
Protein G Purified
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Form
Tissue Culture supernatant, PBS , 0.09% Sodium Azide.
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Concentration
1 mg/ml
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Storage_stability
Store at +4°C or -20°C. Avoid repeated freezing and thawing.
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Tested_application
Immunohistochemistry (IHC), Immunohistochemistry - Paraffin, Immunohistochemistry- Frozen, Western Blot, Flow Cytometry (FC), ELISA (EIA) Optimal dilution to be determined by the researcher.
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Gene
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene. Recombinant. coli interleukin-1o for cell culture or antibody production.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus, Rattus norvegicus