EDAR:Fc, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member EDAR, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, EDA-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)

• Catalog number
  MBS636571
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Active Protein
• Products_short_name
  [EDAR:Fc]
• Specificity
  Binds to human and mouse EDA-A1.
• Purity
  Highly Purified>95% (SDS-PAGE)
• Form
  Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
• Storage_stability
  Short-term Storage: +4 degree CLong-term Storage: -20 degree CStable for at least 6 months after receipt when stored at -20 degree C.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  EDAR   Tumor   Necrosis   Factor   Receptor   Superfamily   Member   EDAR   Anhidrotic   Ectodysplasin   Receptor   Downless   Homolog   EDA-A1   Receptor   Ectodermal   Dysplasia   Receptor   Ectodysplasin-A   Receptor  
• Gene symbol
  EDA, EDAR, RFC4, RFC2, SNAR-A1, PCDHGA1, ZNF2, SCAF1, FALEC, HNRNPA1
• Short name
  EDAR:Fc, Recombinant, (Tumor Necrosis Factor Receptor Superfamily Member EDAR, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, EDA-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Human, CHO cells
• Species
  Human, Humans
• Alternative name
  ectodysplasin A receptor:fragment c, Rec., H. sapiens (Tumor Necrosis Factor Receptor supergroup Member ectodysplasin A receptor, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, ectodysplasin A-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)
• Alternative technique
  rec
• Alternative to gene target
  ectodysplasin A receptor, DL and ECTD10A and ECTD10B and ED1R and ED3 and ED5 and EDA-A1R and EDA1R and EDA3 and HRM1, EDAR and IDBG-65178 and ENSG00000135960 and 10913, protein binding, Plasma membranes, Edar and IDBG-153317 and ENSMUSG00000003227 and 13608, EDAR and IDBG-634358 and ENSBTAG00000019628 and 613947
• Tissue
  tumor

Gene info

• Identity
  HGNC:3157
• Gene
  EDA
• Long gene name
  ectodysplasin A
• Synonyms gene
  • ED1
  • EDA2
  • ODT1
• Synonyms gene name
  • ectodermal dysplasia 1, anhidrotic
  • oligodontia 1
• Synonyms
  • EDA1
  • XLHED
  • HED
  • XHED
  • ED1-A1
  • ED1-A2
  • EDA-A1
  • EDA-A2
• GenBank acession
  • U59227
• Locus
  Xq13.1
• Discovery year
  2001-06-22
• Entrez gene record
  1896
• Pubmed identfication
  • 8696334
  • 18657636
  • 16583127
• RefSeq identity
  • NM_001399
• Classification
  • MicroRNA protein coding host genes
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000021764
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:2895
• Gene
  EDAR
• Long gene name
  ectodysplasin A receptor
• Synonyms gene
  • ED3
  • DL
• Synonyms gene name
  • ectodysplasin 1, anhidrotic receptor
• Synonyms
  • ED5
  • EDA3
  • ED1R
  • EDA1R
• GenBank acession
  • AF130988
• Locus
  2q13
• Discovery year
  1999-08-09
• Entrez gene record
  10913
• Pubmed identfication
  • 10431241
  • 9375732
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000130982

Gene info

• Identity
  HGNC:9972
• Gene
  RFC4
• Long gene name
  replication factor C subunit 4
• Synonyms gene name
  • replication factor C (activator 1) 4 (37kD)
  • replication factor C (activator 1) 4, 37kDa
• Synonyms
  • A1
  • RFC37
• Synonyms name
  • A1 37 kDa subunit
  • activator 1 37 kDa subunit
  • RFC 37 kDa subunit
• Locus
  3q27.3
• Discovery year
  1994-10-14
• Entrez gene record
  5984
• Pubmed identfication
  • 7774928
• RefSeq identity
  • NM_002916
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000156515

Gene info

• Identity
  HGNC:9970
• Gene
  RFC2
• Long gene name
  replication factor C subunit 2
• Synonyms gene name
  • replication factor C (activator 1) 2 (40kD)
  • replication factor C (activator 1) 2, 40kDa
• Synonyms
  • A1
  • RFC40
• Synonyms name
  • activator 1
• Locus
  7q11.23
• Discovery year
  1994-10-14
• Entrez gene record
  5982
• Pubmed identfication
  • 1313560
  • 7774928
• RefSeq identity
  • NM_181471
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000023239

Gene info

• Identity
  HGNC:34304
• Gene
  SNAR-A1
• Long gene name
  small NF90 (ILF3) associated RNA A1
• Synonyms gene name
  • small nuclear ILF3/NF90-associated RNA A1
  • small ILF3/NF90-associated RNA A1
• Synonyms
  • SNAR-A53113498
• GenBank acession
  • EU071051
• Locus
  19q13.33
• Discovery year
  2008-06-20
• Entrez gene record
  100126798
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_004435
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:8696
• Gene
  PCDHGA1
• Long gene name
  protocadherin gamma subfamily A, 1
• Synonyms
  • PCDH-GAMMA-A1
• GenBank acession
  • AF152318
• Locus
  5q31
• Discovery year
  2000-06-28
• Entrez gene record
  56114
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018912
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000163678

Gene info

• Identity
  HGNC:12991
• Gene
  ZNF2
• Long gene name
  zinc finger protein 2
• Synonyms gene name
  • zinc finger protein 2 (A1-5)
• Synonyms
  • A1-5
  • ZNF661
  • Zfp661
• GenBank acession
  • X60152
• Locus
  2q11.1
• Discovery year
  1989-05-31
• Entrez gene record
  7549
• Pubmed identfication
  • 8183940
  • 1945843
• RefSeq identity
  • NM_021088
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000155150

Gene info

• Identity
  HGNC:30403
• Gene
  SCAF1
• Long gene name
  SR-related CTD associated factor 1
• Synonyms
  • SR-A1
  • FLJ00034
• GenBank acession
  • AK024444
• Locus
  19q13.3-q13.4
• Discovery year
  2007-08-09
• Entrez gene record
  58506
• Pubmed identfication
  • 11461075
• RefSeq identity
  • NM_021228
• VEGA ID
  OTTHUMG00000183238

Gene info

• Identity
  HGNC:43713
• Gene
  FALEC
• Long gene name
  focally amplified long non-coding RNA in epithelial cancer
• Synonyms gene
  • LINC00568
• Synonyms gene name
  • long intergenic non-protein coding RNA 568
• Synonyms
  • ncRNA-a1
  • FAL1
• Synonyms name
  • focally amplified lncRNA on chromosome 1
• GenBank acession
  • AL713297
• Locus
  1q21.2
• Discovery year
  2012-02-02
• Entrez gene record
  100874054
• Pubmed identfication
  • 20887892
  • 25203321
  • 29196104
• RefSeq identity
  • NR_051960
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000035849

Gene info

• Identity
  HGNC:5031
• Gene
  HNRNPA1
• Long gene name
  heterogeneous nuclear ribonucleoprotein A1
• Synonyms gene
  • HNRPA1
• Synonyms
  • hnRNP-A1
  • ALS20
• GenBank acession
  • BC009600
• Locus
  12q13.13
• Discovery year
  1991-05-21
• Entrez gene record
  3178
• Pubmed identfication
  • 1733858
  • 23455423
• RefSeq identity
  • NM_031157
• Classification
  • RNA binding motif containing
  • Spliceosomal A complex
  • Heterogeneous nuclear ribonucleoproteins
• VEGA ID
  OTTHUMG00000169702

MeSH Data

• Name
  Gene Knockdown Techniques
• Concept
  Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
• Tree numbers
  • E05.393.335.500
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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