EDAR:Fc, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member EDAR, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, EDA-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)
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Catalog numberMBS636571
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Price:
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Size0.05 mg
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Products_typeActive Protein
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Products_short_name[EDAR:Fc]
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SpecificityBinds to human and mouse EDA-A1.
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PurityHighly Purified>95% (SDS-PAGE)
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FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
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Storage_stabilityShort-term Storage: +4 degree CLong-term Storage: -20 degree CStable for at least 6 months after receipt when stored at -20 degree C.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolEDA, EDAR, RFC4, RFC2, SNAR-A1, PCDHGA1, ZNF2, SCAF1, HNRNPA1, FALEC
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Short nameEDAR:Fc, Recombinant, (Tumor Necrosis Factor Receptor Superfamily Member EDAR, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, EDA-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)
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TechniqueRecombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostHuman, CHO cells
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SpeciesHuman, Humans
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Alternative nameectodysplasin A receptor:fragment c, Rec., H. sapiens (Tumor Necrosis Factor Receptor supergroup Member ectodysplasin A receptor, Anhidrotic Ectodysplasin Receptor 1, Downless Homolog, ectodysplasin A-A1 Receptor, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor)
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Alternative techniquerec
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Alternative to gene targetectodysplasin A receptor, DL and ECTD10A and ECTD10B and ED1R and ED3 and ED5 and EDA-A1R and EDA1R and EDA3 and HRM1, EDAR and IDBG-65178 and ENSG00000135960 and 10913, protein binding, Plasma membranes, Edar and IDBG-153317 and ENSMUSG00000003227 and 13608, EDAR and IDBG-634358 and ENSBTAG00000019628 and 613947
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameectodysplasin A
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Synonyms gene
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Synonyms gene name
- ectodermal dysplasia 1, anhidrotic
- oligodontia 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameectodysplasin A receptor
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Synonyms gene
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Synonyms gene name
- ectodysplasin 1, anhidrotic receptor
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-08-09
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namereplication factor C subunit 4
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Synonyms gene name
- replication factor C (activator 1) 4 (37kD)
- replication factor C (activator 1) 4, 37kDa
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-10-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AAA ATPases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namereplication factor C subunit 2
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Synonyms gene name
- replication factor C (activator 1) 2 (40kD)
- replication factor C (activator 1) 2, 40kDa
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-10-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AAA ATPases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall NF90 (ILF3) associated RNA A1
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Synonyms gene name
- small nuclear ILF3/NF90-associated RNA A1
- small ILF3/NF90-associated RNA A1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-06-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small NF90 (ILF3) associated RNAs
Gene info
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Identity
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Gene
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Long gene nameprotocadherin gamma subfamily A, 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-06-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Clustered protocadherins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger protein 2
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Synonyms gene name
- zinc finger protein 2 (A1-5)
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSR-related CTD associated factor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-08-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein A1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-05-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Spliceosomal A complex
- Heterogeneous nuclear ribonucleoproteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefocally amplified long non-coding RNA in epithelial cancer
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Synonyms gene
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Synonyms gene name
- long intergenic non-protein coding RNA 568
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2012-02-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
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Tree numbers
- E05.393.335.500
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data