-
Products_type
Active Protein
-
Products_short_name
[Axl]
-
Other_names
[AXL receptor tyrosine kinase, isoform CRA_b; Tyrosine-protein kinase receptor UFO; tyrosine-protein kinase receptor UFO; AXL oncogene; AXL transforming sequence/gene; AXL receptor tyrosine kinase; AXL oncogene]
-
Other_gene_names
[AXL; AXL; UFO; JTK11; UFO]
-
Purity
Purified70% by SDS-PAGE
-
Form
Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 100mM NaCl, 0.05% Tween-20, 50% glycerol and 3mM DTT.
-
Storage_stability
Aliquot to avoid repeated freezing and thawing and store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
-
Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Axl, Recombinant, (AXL Oncogene, AXL Receptor Tyrosine Kinase, AXL Transforming , AXL Transforming Sequence/ , Adhesion- Kinase, Ark, Oncogene AXL, Tyrosine Protein Kinase Receptor, UFO, TYR07). cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
AXL
-
Short name
Axl, Recombinant, (AXL Oncogene, AXL Receptor Tyrosine Kinase, AXL Transforming , AXL Transforming Sequence/ , Adhesion- Kinase, Ark, Oncogene AXL, Tyrosine Protein Kinase Receptor, UFO, TYR07)
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Host
Baculovirus infected Sf9 cells
-
Species
Human, Humans
-
Alternative name
Axl, Rec., H. sapiens (AXL Oncogene, AXL Receptor Tyrosine phosphorylation catalyst, AXL Transforming Gene, AXL Transforming Sequence/gene, Adhesion-related phosphorylation catalyst, Ark, Oncogene AXL, Tyrosine Protein phosphorylation catalyst Receptor, UFO, TYR07)
-
Alternative technique
rec
-