Caspase 8

MeSH code information

• Name
  Caspase 8
• Concept
  Registry number: EC 3.4.22.-

  Scope note: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
• Tree numbers
  • D08.811.277.656.262.500.126.550.800
  • D08.811.277.656.300.200.126.550.800
  • D12.644.360.024.285.037
  • D12.644.360.075.405.550.800
  • D12.644.360.075.421.037
  • D12.776.157.057.018.037
  • D12.776.476.024.320.025
  • D12.776.476.075.405.550.800
  • D12.776.476.075.421.037
• Qualifiers
  isolation & purification, immunology, pharmacokinetics, biosynthesis, physiology, therapeutic use, blood, cerebrospinal fluid, chemical synthesis, chemistry, drug effects, urine, radiation effects, history, analysis, classification, economics, genetics, pharmacology, standards, administration & dosage, supply & distribution, ultrastructure, poisoning, adverse effects, toxicity, metabolism