Signaling Lymphocytic Activation Molecule Family

MeSH code information
  • Name
  • Concept
    Scope note:Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.
  • Tree numbers
    • D12.776.395.550.736
    • D12.776.543.550.746
    • D12.776.543.750.705.970
    • D23.050.301.264.035.915
    • D23.101.100.110.935
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Signaling Lymphocytic Activation Molecule Family - MeSH Info
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