Cytochrome P-450 CYP11B2
MeSH code information
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Name
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ConceptRegistry number: EC 1.14.15.4Scope note: A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
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Tree numbers
- D08.244.453.484.500
- D08.244.453.915.050
- D08.811.682.690.708.170.425.500
- D08.811.682.690.708.170.915.050
- D12.776.422.220.453.484.500
- D12.776.422.220.453.915.050
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Qualifiersisolation & purification, immunology, pharmacokinetics, biosynthesis, physiology, therapeutic use, blood, cerebrospinal fluid, chemical synthesis, deficiency, chemistry, drug effects, urine, radiation effects, history, analysis, classification, economics, genetics, pharmacology, standards, administration & dosage, antagonists & inhibitors, supply & distribution, ultrastructure, poisoning, adverse effects, toxicity, metabolism