D-Serine Dehydratase belongs to the β- family of the Pyridoxal phosphate-dependent enzymes and part of the fold-type II family. It binds to one catalytically essential PLP per protein molecule but also contains another low affinity PLP binding site. The enzyme converts D-Serine, D-threonine, D-allo-Threonine to corresponding α-keto acid and ammonia. It is suggested to act as a detoxifying enzyme for E.Coli strains.
Specific targetted sequence
Molecular weight (in Da)
DsdSC, D-serine deaminase, DSD, DSD1
SDS-PAGE (Purity > 95% )
The specific activity (specifications/test method) was measured by its ability to metabolizes 1 μmole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
The specific bioactivity is ≥ 60 mU/mg
Expected results ≥ 60 mU/mg
One Unit of DsdSC metabolizes 1 μmole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
Handling and storage
Centrifuge the vial prior to opening. Store for 12 months at -20°C
Shipped under gel pack
This product is supplied as lyophilized form from 50 mM Sodium phosphate, pH 7.0, 30% glycerol
Reconstitute in 50 mM potassium phosphate, 50 mM NaCl, pH 7.4.
Manufactured in USA. For Research Use Only! Not to be used in humans
Manifactured since May 2017. Available to order. Please contact us for larger or bulk quantity
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.