Rat anti Interleukin-6

• Catalog number
  X1946M
• Price
  Please ask
• Size
  500 μg

• Category
  Primary Antibodies
• Long description
  IL-6 (MP5-20F3) RTXMS; Unconjugated Monoclonal antibody specific to Mouse IL-6. This antibody is validated for use in Flow Cytometry, Immunoassay (ELISA). Anti-IL-6 recognizes the expressed product of the Il6 gene.
• Antibody come from
  Recombinant human p70-S6K protein.
• Other description
  Provided as solution in phosphate buffered saline, pH 7.3, with 1% BSA and 0.08% sodium azide. Protein A/G Chromatography
• Clone
  MP5-20F3
• Antigen antibody binding interaction
  Rat anti Interleukin-6 Antibody
• Antibody is raised in
  Rat
• Antibody s reacts with
  Mouse
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  ELISA s a coating antibody, Western Blot, Immunohistochemistry, Neutralization, Flow Cytometry
• Antibody s suited for
  Antibody can be used for Western blotting (0.5-1 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Tu, V.C., et al. (2002) Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase. J. Pharmacol. Exp. Ther. 300(3):1101-1110._x000B__x000B_2. Zhang, Y., et al. (2001) Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation. DNA Cell. Biol. 20(12):769-779._x000B__x000B_3. Gonzalez-Garcia, A., et al. (2002) A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation. J. Biol. Chem. 277(2):1500-1508.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus

• Gene target
  Interleukin-6  
• Gene symbol
  IL6RP1, IL6, IL6STP1
• Short name
  anti Interleukin-6
• Technique
  anti, antibody to
• Host
  Rat
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Rat, Rats
• Alternative name
  Rat antibody to Interleukin-6
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6020
• Gene
  IL6RP1
• Long gene name
  interleukin 6 receptor pseudogene 1
• Synonyms gene
  • IL6RL1
• Synonyms gene name
  • interleukin 6 receptor-like 1
• Locus
  9q22.2
• Discovery year
  1991-08-18
• Entrez gene record
  157916
• Pubmed identfication
  • 1889804
• RefSeq identity
  • NG_002785
• VEGA ID
  OTTHUMG00000020190

Gene info

• Identity
  HGNC:6018
• Gene
  IL6
• Long gene name
  interleukin 6
• Synonyms gene
  • IFNB2
• Synonyms gene name
  • interleukin 6 (interferon, beta 2)
• Synonyms
  • IL-6
  • BSF2
  • HGF
  • HSF
• Synonyms name
  • interferon, beta 2
• GenBank acession
  • M18403
• Locus
  7p15.3
• Discovery year
  1986-01-01
• Entrez gene record
  3569
• Pubmed identfication
  • 3294161
• RefSeq identity
  • NM_000600
• Classification
  • Interleukins
  • Interferons
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000023178

Gene info

• Identity
  HGNC:6022
• Gene
  IL6STP1
• Long gene name
  interleukin 6 signal transducer pseudogene 1
• Synonyms gene
  • IL6STP
• Synonyms gene name
  • interleukin 6 signal transducer (gp130, oncostatin M receptor) pseudogene
  • interleukin 6 signal transducer (gp130, oncostatin M receptor) pseudogene 1
• Locus
  17p12
• Discovery year
  1995-05-16
• Entrez gene record
  3573
• Pubmed identfication
  • 7736792
• RefSeq identity
  • NG_002748
• VEGA ID
  OTTHUMG00000059144

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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