Caspase-1 / ICE Inhibitor 2 (Z-YVAD-FMK)
Catalog number
AB-011
Supplier
Price
644.27 USD
Size
3 mg
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene target
Gene symbol
PSMB7, CASP1, PLA2G4F, HLA-Z, CASP5, CES2, CARD18, CASP9, CARD16, CASP4
Short name
Caspase-1 / ICE Inhibitor 2 (Z-YVAD-FMK)
Alternative name
caspase-1 / ICE suppressor 2 (Z-YVAD-FMK)
Gene info
Gene info
Identity
Gene
Long gene name
caspase 1
Synonyms gene
Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
Synonyms
Synonyms name
GenBank acession
Locus
Discovery year
1992-05-07
Entrez gene record
Pubmed identfication
RefSeq identity
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID
Gene info
Gene info
Gene info
Identity
Gene
Long gene name
caspase 5
Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
Synonyms
Locus
Discovery year
1996-09-13
Entrez gene record
Pubmed identfication
RefSeq identity
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID
Gene info
Identity
Gene
Long gene name
carboxylesterase 2
Synonyms gene name
- carboxylesterase 2 (intestine, liver)
Synonyms
GenBank acession
Locus
Discovery year
1993-09-30
Entrez gene record
Pubmed identfication
RefSeq identity
Classification
VEGA ID
Gene info
Gene info
Identity
Gene
Long gene name
caspase 9
Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
Synonyms
Synonyms name
GenBank acession
Locus
Discovery year
1996-11-11
Entrez gene record
Pubmed identfication
RefSeq identity
Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID
Gene info
Gene info
Identity
Gene
Long gene name
caspase 4
Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
Synonyms
GenBank acession
Locus
Discovery year
1996-07-22
Entrez gene record
Pubmed identfication
RefSeq identity
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID
MeSH Data
Name
Concept
Scope note:Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
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