EpiGentek

Epigentek Group Inc., established in 2005, is a leading epigenetics company dedicated to developing innovative technologies and products for epigenetics-related research and drug discovery. With a comprehensive portfolio of proprietary solutions, Epigentek aims to provide systematic and complete support to researchers in academia, pharmaceuticals, and biotechnology worldwide.

Designed for simplicity, speed, and efficiency, Epigentek’s unique products streamline assays, outperforming traditional methods in convenience and performance. These cutting-edge tools are distributed globally through a dedicated sales team and an extensive network spanning over 36 countries and regions.

Committed to customer satisfaction and experimental success, Epigentek prioritizes technological innovation and continues to expand and refine its product offerings, solidifying its position as a pioneer in the field of epigenetics.

Browse EpiGentek Products

2-Hydroxyisobutyryl HIST1H3A (K122) Polyclonal Antibody

SKU: A70364-050|Size: 50 µL

2-hydroxyisobutyryl HIST1H3A (K23) Polyclonal Antibody

SKU: A70391-050|Size: 50 µL

2-hydroxyisobutyryl HIST1H3A (K56) Polyclonal Antibody

SKU: A69379-100|Size: 100 µL

2-hydroxyisobutyryl HIST1H4A (K31) Polyclonal Antibody

SKU: A70392-100|Size: 100 µL

5-Aza-2'-deoxycytidine

SKU: M22000|Size: 50 mg

5-Azacytidine

SKU: M22001|Size: 1 g

5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]

SKU: A-1018-010|Size: 10 µg

5-Hydroxymethyluridine Polyclonal Antibody

SKU: A-1300|Size: 0.1 mL

5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]

SKU: A-1014-100|Size: 100 µg

8-Hydroxyguanosine (8-OHG) Polyclonal Antibody

SKU: A-6300|Size: 0.1 mL

A4GNT Polyclonal Antibody

SKU: A62026-100|Size: 100 µL

A4GNT Polyclonal Antibody, Biotin Conjugated

SKU: A62029-050|Size: 50 µL

A4GNT Polyclonal Antibody, FITC Conjugated

SKU: A62028-100|Size: 100 µL

A4GNT Polyclonal Antibody, HRP Conjugated

SKU: A62027-050|Size: 50 µL

AADAC Polyclonal Antibody

SKU: A71885-050|Size: 50 µL

AADAC Polyclonal Antibody, Biotin Conjugated

SKU: A57919-050|Size: 50 µL

AADAC Polyclonal Antibody, FITC Conjugated

SKU: A57920-100|Size: 100 µL

AADAC Polyclonal Antibody, HRP Conjugated

SKU: A57921-050|Size: 50 µL

AADACL2 Polyclonal Antibody

SKU: A62030-020|Size: 20 µL

AADACL2 Polyclonal Antibody, Biotin Conjugated

SKU: A62033-100|Size: 100 µL

AADACL2 Polyclonal Antibody, FITC Conjugated

SKU: A62032-100|Size: 100 µL

AADACL2 Polyclonal Antibody, HRP Conjugated

SKU: A62031-050|Size: 50 µL

AADAT Polyclonal Antibody

SKU: A66746-100|Size: 100 µL

AADAT Polyclonal Antibody, Biotin Conjugated

SKU: A66749-050|Size: 50 µL

AADAT Polyclonal Antibody, FITC Conjugated

SKU: A66748-100|Size: 100 µL

AADAT Polyclonal Antibody, HRP Conjugated

SKU: A66747-050|Size: 50 µL

AANAT Polyclonal Antibody

SKU: A69907-020|Size: 20 µL

AANAT Polyclonal Antibody, Biotin Conjugated

SKU: A69910-100|Size: 100 µL

AANAT Polyclonal Antibody, FITC Conjugated

SKU: A69909-100|Size: 100 µL

AANAT Polyclonal Antibody, HRP Conjugated

SKU: A69908-100|Size: 100 µL

AAO Polyclonal Antibody

SKU: A55231-050|Size: 50 µL

AAO Polyclonal Antibody, Biotin Conjugated

SKU: A55234-100|Size: 100 µL

AAO Polyclonal Antibody, FITC Conjugated

SKU: A55233-100|Size: 100 µL

AAO Polyclonal Antibody, HRP Conjugated

SKU: A55232-100|Size: 100 µL

AAP1 Polyclonal Antibody

SKU: A64314-050|Size: 50 µL

AAP1 Polyclonal Antibody, Biotin Conjugated

SKU: A64317-100|Size: 100 µL

AAP1 Polyclonal Antibody, FITC Conjugated

SKU: A64316-100|Size: 100 µL

AAP1 Polyclonal Antibody, HRP Conjugated

SKU: A64315-100|Size: 100 µL

AAR2 Polyclonal Antibody

SKU: A57922-100|Size: 100 µL

AAR2 Polyclonal Antibody, Biotin Conjugated

SKU: A57923-100|Size: 100 µL

AAR2 Polyclonal Antibody, FITC Conjugated

SKU: A57924-100|Size: 100 µL

AAR2 Polyclonal Antibody, HRP Conjugated

SKU: A57925-050|Size: 50 µL

AARS Polyclonal Antibody

SKU: A68447-020|Size: 20 µL

AARS Polyclonal Antibody, Biotin Conjugated

SKU: A68450-050|Size: 50 μL

AARS Polyclonal Antibody, FITC Conjugated

SKU: A68449-100|Size: 100 µL

AARS Polyclonal Antibody, HRP Conjugated

SKU: A68448-100|Size: 100 µL

AARSD1 Polyclonal Antibody

SKU: A57926-020|Size: 20 µL

AARSD1 Polyclonal Antibody, Biotin Conjugated

SKU: A57927-100|Size: 100 µL

AARSD1 Polyclonal Antibody, FITC Conjugated

SKU: A57928-100|Size: 100 µL

AARSD1 Polyclonal Antibody, HRP Conjugated

SKU: A57929-050|Size: 50 µL

AASDHPPT Polyclonal Antibody

SKU: A71769-050|Size: 50 µL

AASDHPPT Polyclonal Antibody, Biotin Conjugated

SKU: A56786-100|Size: 100 µL

AASDHPPT Polyclonal Antibody, FITC Conjugated

SKU: A56785-050|Size: 50 µL

AASDHPPT Polyclonal Antibody, HRP Conjugated

SKU: A56784-100|Size: 100 µL

AATF Polyclonal Antibody

SKU: A51673-100|Size: 100 µL

AATF Polyclonal Antibody, Biotin Conjugated

SKU: A51676-100|Size: 100 µL

AATF Polyclonal Antibody, FITC Conjugated

SKU: A51675-100|Size: 100 µL

AATF Polyclonal Antibody, HRP Conjugated

SKU: A51674-050|Size: 50 µL

ABAT Recombinant Monoclonal Antibody [5B6]

SKU: A74509-100|Size: 100 µL

ABCA12 Polyclonal Antibody

SKU: A69003-020|Size: 20 µL

ABCA12 Polyclonal Antibody, Biotin Conjugated

SKU: A69006-100|Size: 100 µL

ABCA12 Polyclonal Antibody, FITC Conjugated

SKU: A69005-100|Size: 100 µL

ABCA12 Polyclonal Antibody, HRP Conjugated

SKU: A69004-050|Size: 50 μL

ABCA9 Polyclonal Antibody

SKU: A66090-020|Size: 20 µL

ABCA9 Polyclonal Antibody, Biotin Conjugated

SKU: A66093-100|Size: 100 µL

ABCA9 Polyclonal Antibody, FITC Conjugated

SKU: A66092-100|Size: 100 µL

ABCA9 Polyclonal Antibody, HRP Conjugated

SKU: A66091-050|Size: 50 µL

ABCB1 Polyclonal Antibody

SKU: A52229-050|Size: 50 µL

ABCB1 Polyclonal Antibody, Biotin Conjugated

SKU: A52226-100|Size: 100 µL

ABCB1 Polyclonal Antibody, FITC Conjugated

SKU: A52227-100|Size: 100 µL

ABCB1 Polyclonal Antibody, HRP Conjugated

SKU: A52228-050|Size: 50 µL

ABCB1 Recombinant Monoclonal Antibody [11H10]

SKU: A74579-100|Size: 100 µL

ABCB5 Polyclonal Antibody

SKU: A57930-020|Size: 20 µL

ABCB5 Polyclonal Antibody, Biotin Conjugated

SKU: A57931-100|Size: 100 µL

ABCB5 Polyclonal Antibody, FITC Conjugated

SKU: A57932-050|Size: 50 µL

ABCB5 Polyclonal Antibody, HRP Conjugated

SKU: A57933-050|Size: 50 µL

ABCF2 Polyclonal Antibody

SKU: A73654-100|Size: 100 µL

ABCF3 Polyclonal Antibody

SKU: A71887-050|Size: 50 µL

ABCF3 Polyclonal Antibody, Biotin Conjugated

SKU: A57935-050|Size: 50 µL

ABCF3 Polyclonal Antibody, FITC Conjugated

SKU: A57936-050|Size: 50 µL

ABCF3 Polyclonal Antibody, HRP Conjugated

SKU: A57937-100|Size: 100 µL

ABHD14A Polyclonal Antibody

SKU: A57942-020|Size: 20 µL

ABHD14A Polyclonal Antibody, Biotin Conjugated

SKU: A57943-050|Size: 50 µL

ABHD14A Polyclonal Antibody, FITC Conjugated

SKU: A57944-100|Size: 100 µL

ABHD14A Polyclonal Antibody, HRP Conjugated

SKU: A57945-100|Size: 100 µL

ABHD14B Polyclonal Antibody

SKU: A57377-020|Size: 20 µL

ABHD14B Polyclonal Antibody, Biotin Conjugated

SKU: A57380-100|Size: 100 µL

ABHD14B Polyclonal Antibody, FITC Conjugated

SKU: A57379-100|Size: 100 µL

ABHD14B Polyclonal Antibody, HRP Conjugated

SKU: A57378-050|Size: 50 µL

ABHD18 Polyclonal Antibody

SKU: A64610-100|Size: 100 µL

ABHD18 Polyclonal Antibody, Biotin Conjugated

SKU: A64613-100|Size: 100 µL

ABHD18 Polyclonal Antibody, FITC Conjugated

SKU: A64612-100|Size: 100 µL

ABHD18 Polyclonal Antibody, HRP Conjugated

SKU: A64611-100|Size: 100 µL

ABHD2 Polyclonal Antibody

SKU: A57946-100|Size: 100 µL

ABHD2 Polyclonal Antibody, Biotin Conjugated

SKU: A57947-100|Size: 100 µL

ABHD2 Polyclonal Antibody, FITC Conjugated

SKU: A57948-050|Size: 50 µL

ABHD2 Polyclonal Antibody, HRP Conjugated

SKU: A57949-050|Size: 50 µL

ABHD3 Polyclonal Antibody

SKU: A51129-050|Size: 50 µL

ABHD3 Polyclonal Antibody, Biotin Conjugated

SKU: A51132-050|Size: 50 µL

ABHD3 Polyclonal Antibody, FITC Conjugated

SKU: A51131-100|Size: 100 µL

Our Mission

To build and become the world-leading, complete and systematic provider of epigenetic-related products, technologies, and services through innovative and intelligent research and development. Our objectives are to: Assist researchers in solving challenges in epigenetic issues. Develop and introduce simplification and accuracy to epigenetic experiments. Ensure customer satisfaction through superior reliability, speed, service, and quality. Encourage and facilitate the study of epigenetics for potential medical applications. Pioneer and innovate epigenetic products through routine analysis of technological trends.

Chromatin Studies Step Details : Chromatin Isolation:

Chromatin, a complex of DNA and proteins, plays a crucial role in compacting DNA to fit within the cell, safeguarding it from damage, and regulating gene expression and DNA replication. High-quality chromatin isolation is essential for assays that investigate protein-DNA interactions. Epigentek's proprietary chromatin isolation kits provide reliable solutions for isolating intact chromatin, utilizing versatile methods to extract chromatin efficiently from both mammalian and plant cells and tissues.

Chromatin Studies Step Details : Chromatin Accessibility:

Chromatin structure plays a critical role in gene regulation, largely determined by its accessibility to transcription factors and other DNA-binding proteins. Typically, highly condensed chromatin restricts access, making it challenging for these proteins to interact with DNA and perform their functions. Conversely, more accessible chromatin correlates with active transcription of nearby genes. Investigating chromatin accessibility is particularly valuable for understanding the presence or absence of nucleosomes, which directly or indirectly influence numerous cellular and metabolic processes.

EpiQuik Chromatin Accessibility Assay Kit

SKU: P-1047|Size: 48 Assays

Chromatin Studies Step Details : Chromatin Fragmentation :

Ultrasonic energy processing has become a widely preferred alternative to enzymatic digestion for chromatin samples. With a focus on high-throughput processing and minimizing sample contamination, our EpiSonic™ sonicators seamlessly integrate into existing laboratory workflows. They are particularly well-suited for applications in epigenetics and next-generation sequencing, offering reliability and compatibility for advanced research needs.

EpiSonic 2000 Sonication System

SKU: EQC-2000|Size: Each

Chromatin Studies Step Details : Chromatin Immunoprecipitation (ChIP):

Protein-DNA interactions are essential for cellular functions, making it critical to identify the genetic targets of DNA-binding proteins and understand the mechanisms behind these interactions. Chromatin Immunoprecipitation (ChIP) is a powerful tool for studying these processes, offering a unique advantage over other methods by enabling the detection of specific protein bindings to precise gene sequences in living cells. To support researchers, Epigentek offers a range of assay kits designed to facilitate efficient, accurate, and reproducible ChIP-based experiments in the lab.

EpiQuik Chromatin Immunoprecipitation (ChIP) Kit

SKU: P-2002|Size: 96 Reactions

ChromaFlash High-Sensitivity ChIP Kit

SKU: P-2027|Size: 48 Reactions

EpiQuik Plant ChIP Kit

SKU: P-2014|Size: 48 Reactions

Chromatin Studies Step Details : PCR / Sequencing (ChIP-Seq) NGS Analysis :

Taking the process a step further, NGS (Next Generation Sequencing) technologies have increased data output volumes and lowered the cost of ChIP-sequencing. ChIP-Seq offers a combination of the chromatin immunoprecipitation process already discussed paired with next generation sequencing methods to offer an effective method for identifying genome-wide DNA binding sites of transcriptions factors and other proteins. ChIP-Seq offers the benefit of resolving the specific genetic sequence of target protein binding sites on a genome-wide level. Real-time quantitative PCR (RT-qPCR) offers an alternative approach by analyzing the binding sites of modified histones and/or other DNA-binding proteins at precise loci using selective amplification with specific primers. EpiGentek offers various inexpensive solutions for both PCR & NGS, including full package kits to conveniently construct high quality DNA libraries from low quantity or difficult samples.

EpiNext ChIP-Seq High-Sensitivity Kit (Illumina)

SKU: P-2030|Size: 24 Reactions

Chromatin Studies Step Details : CUT&RUN-Fast / CUT&TAG In-Place:

In recent years, developments have been made that are revolutionizing how researchers perform DNA-protein interaction analysis through a process called CUT&RUN. Standing for Cleavage Under Target & Release Using Nuclease, the process was developed to release the captured target protein/DNA complex from limited biological materials for mapping protein-DNA interaction and has significantly improved mapping resolution. This process has been refined with the new CUT&RUN-Fast, which allows for less input materials to be used while limiting background signals. And as an extension, cTIP (CUT & Tag In Place), adds the step of preparing a library for next generation sequencing and provide a similar solution to ChIP-Seq with all the benefits previously mentioned. As the research landscape changes, CUT&RUN-Fast and cTIP are poised to become increasingly popular methods of DNA-protein interaction studies, given their wide range of benefits.

EpiNext CUT&RUN Fast Kit

SKU: P-2028|Size: 24 Reactions

EpiNext CUT&Tag In-Place (cTIP) Seq Kit

SKU: P-2032|Size: 12 Reactions

Histone Studies Step Details : Histone Extraction:

The EpiQuik Total Histone Extraction Kits provide a fast and reliable method for isolating histone proteins from mammalian cells or tissues in just one hour. Ideal for preparing histone extracts, these kits are highly recommended for use with Epigentek’s histone modification assay kits or for various downstream applications, including studies of histone acetylation, methylation, phosphorylation, and sumoylation.

Histone Studies Step Details : Nuclear Extraction :

The EpiQuik Nuclear Extraction Kits offer a quick and reliable solution for isolating nuclear proteins from cells or tissues in just one hour. These high-quality extracts are compatible with EpiGentek’s DNMT, HMT, Histone Demethylase, HDAC, and HAT kits, as well as a wide range of applications such as Western blotting, protein-DNA binding assays, nuclear enzyme assays, and other procedures requiring optimized nuclear proteins.

EpiQuik Nuclear Extraction Kit

SKU: OP-0002|Size: 100 Assays

Histone Studies Step Details : Histone H3 & H4 Multiplex Assays :

The EpiQuik Histone H3 and H4 Modification Multiplex Assay Kits provide a comprehensive overview of your sample's histone modification profile. Using a convenient ELISA-like method that only requires a standard microplate reader, these kits allow you to simultaneously measure 21 distinct histone H3 modifications, 10 histone H4 modifications, or 22 circulating histone H3 modifications. Each kit includes the most significant and well-characterized histone modification patterns, helping you save time and resources while achieving reliable results.

EpiQuik Histone H3 Modification Multiplex Assay Kit (Colorimetric)

SKU: P-3100|Size: 96 Assays

EpiQuik Histone H4 Modification Multiplex Assay Kit (Colorimetric)

SKU: P-3102|Size: 96 Assays

EpiQuik Circulating Modified Histone H3 Multiplex Assay Kit (Colorimetric)

SKU: P-3106|Size: 96 Assays

Methylation

The MethylFlash Easy kits retain the key benefits of previous versions while introducing a simplified "one-step" ELISA reaction that eliminates the need for multiple sample and antibody binding steps. With streamlined protocols, these kits reduce procedure times by 50% compared to the earlier MethylFlash kits. Adjustments have also been made to minimize the CV% between wells. The improved "signal window" and updated calculation formulas enhance the accuracy of the results. In summary, MethylFlash Easy kits are faster, easier to use, more reliable, and provide more accurate outcomes.

MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit (Colorimetric)

SKU: P-1030|Size: 96 Reactions

MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit (Colorimetric)

SKU: P-1032|Size: 96 Reactions

BisulPlus Loci 5mC & 5hmC Detection PCR Kit

SKU: P-1067|Size: 2 x 24 Reactions

Methylamp Methylated DNA Capture (MeDIP) Kit

SKU: P-1015|Size: 48 Reactions

EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit

SKU: P-1038|Size: 96 Reactions

EpiNext RRBS Library Fast Kit

SKU: P-1069|Size: 12 Reactions

RNA Methylation Studies Step Details :

RNA Isolation Isolating RNA is a crucial initial step in RNA methylation studies. Our RNA preparation kits offer a fast and efficient method for isolating total RNA directly from a variety of samples, including tissue, cultured cells, and cell-free liquid specimens such as saliva and nasopharyngeal swabs. The purified RNA can then be used in a range of standard applications, including RT-PCR, cDNA synthesis, Northern blotting, differential display, primer extension, and mRNA selection. Global m6A & 5mC RNA Quantification EpiGentek's m6A and 5mC RNA methylation kits simplify the process for researchers to investigate the impact of RNA methylation on their studies. These kits enable the direct quantification of N6-Methyladenosine (m6A) or global 5-methylcytosine (5mC) RNA, using total RNA isolated from a variety of species, including mammals, plants, fungi, bacteria, and viruses. RNA Bisulfite Conversion & cDNA Synthesis Bisulfite treatment, also referred to as bisulfite conversion, is an optimal method for preparing RNA for site-specific methylation analysis. This technique converts cytosine to uracil, while leaving methylated cytosine unchanged, allowing for easy identification through high-throughput sequencing. Bisulfite-converted RNA can also be used to generate cDNA for various downstream applications to assess methylation status.

EpiNext 5-mC RNA Bisulfite-Seq Easy Kit (Illumina)

SKU: P-9007|Size: 12 Reactions

EpiNext Hi-Fi cDNA Synthesis Kit

SKU: P-9004|Size: 20 Samples

EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)

SKU: P-9005|Size: 96 Reactions

MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)

SKU: P-9009|Size: 48 Reactions

MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric)

SKU: P-9015|Size: 96 Assays

EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)

SKU: P-9008|Size: 96 Assays

DNA Methylation studies step details:

Global DNA Methylation Kits The MethylFlash Easy kits maintain the key advantages of previous versions while introducing a streamlined "one-step" ELISA reaction that eliminates the need for multiple sample and antibody binding steps. The simplified protocols cut procedure times by 50% compared to the earlier MethylFlash kits. Additional adjustments have been made to reduce the CV% between wells. With an expanded "signal window" and refined calculation formulas, these new kits offer enhanced accuracy. In summary, MethylFlash Easy kits are faster, easier to use, more reliable, and provide highly accurate results. Site-Specific & Genome-Wide DNA Methylation Assays DNA methylation is a key epigenetic modification that regulates gene expression and is linked to various biological processes and diseases. Site-specific DNA methylation assays focus on methylation at particular genomic regions, helping to study gene regulation and disease mechanisms. In contrast, genome-wide DNA methylation assays provide a broader view of methylation patterns across the entire genome, identifying differentially methylated regions linked to diseases or environmental factors. Both approaches are crucial for understanding epigenetic regulation and its role in health and disease. DNMT & DNA Demethylase Kits DNMT and DNA demethylase kits are designed to study the enzymes involved in DNA methylation regulation. DNMT kits measure the activity of DNA methyltransferases, which add methyl groups to DNA, influencing gene expression. DNA demethylase kits focus on enzymes that remove these methyl groups, potentially activating gene expression. Both kits are essential for understanding epigenetic changes in health, disease, and therapeutic research.

MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit (Colorimetric)

SKU: P-1030|Size: 96 Reactions

MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit (Colorimetric)

SKU: P-1032|Size: 96 Reactions

BisulPlus Loci 5mC & 5hmC Detection PCR Kit

SKU: P-1067|Size: 2 x 24 Reactions

Methylamp Methylated DNA Capture (MeDIP) Kit

SKU: P-1015|Size: 48 Reactions

EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit

SKU: P-1038|Size: 96 Reactions

EpiNext RRBS Library Fast Kit

SKU: P-1069|Size: 12 Reactions

EpiQuik DNMT Activity/Inhibition ELISA Easy Kit (Colorimetric)

SKU: P-3139|Size: 48 Assays

EpiQuik DNA Demethylase Activity/Inhibition Assay Ultra Kit

SKU: P-3008|Size: 96 Assays

Epigenase 5mC-Hydroxylase TET Activity/Inhibition Assay Kit (Colorimetric)

SKU: P-3086|Size: 96 Assays

Epigenase 5mC-Hydroxylase TET Activity/Inhibition Assay Kit (Fluorometric)

SKU: P-3087|Size: 96 Assays

Epigenase Thymine DNA Glycosylase (TDG) Activity/Inhibition Assay Kit (Colorimetric)

SKU: P-3094|Size: 96 Assays