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Cytoskeleton

The cytoskeleton is a dynamic network of protein filaments and tubules that extends throughout the cytoplasm of eukaryotic cells. It provides structural support, facilitates intracellular transport, enables cellular movement, and plays essential roles in cell division and signaling. ​


Key Components:

Microfilaments (Actin Filaments):

Structure: Thin, flexible fibers composed of actin proteins.

Functions: Maintain cell shape, enable cell motility, facilitate muscle contraction, and support intracellular transport

Intermediate Filaments:

Structure: Stable, rope-like fibers made of various proteins, such as vimentin, keratins, and neurofilaments.​

Functions: Provide mechanical strength, maintain cell integrity, and anchor organelles in place.​

Microtubules:

Structure: Hollow tubes composed of tubulin dimers.

Functions: Determine cell shape, facilitate intracellular transport (serving as tracks for motor proteins like kinesin and dynein), and form structures like cilia and flagella for cell movement

Browse Cytoskeleton Products
ARNO GEF Protein (Sec7 Exchange Domain - aa31-267 - 6xHis tag)

ARNO GEF Protein (Sec7 Exchange Domain - aa31-267 - 6xHis tag)

SKU: CS-GE07|Size: 1x 100 µg

ATP - 100mM stock

ATP - 100mM stock

SKU: BSA04-001|Size: 1x 1 mL

ATPase/GTPase ELIPA™ (Enzyme Linked Inorganic Phosphate Assay)

ATPase/GTPase ELIPA™ (Enzyme Linked Inorganic Phosphate Assay)

SKU: BK051/52|Size: 96 Assays/Kit

Acetyl Lysine Antibody Mouse Monoclonal

Acetyl Lysine Antibody Mouse Monoclonal

SKU: AAC01-S|Size: 1x 25 µL

Acetyl-Lysine Affinity Beads - AAC02

Acetyl-Lysine Affinity Beads - AAC02

SKU: AAC02-beads|Size: 4x 500 µL

Acetyl-Lysine Affinity Beads - AAC03

Acetyl-Lysine Affinity Beads - AAC03

SKU: AAC03-beads-L|Size: 4x 500 µL

Acetyl-Lysine Affinity Beads - AAC04

Acetyl-Lysine Affinity Beads - AAC04

SKU: AAC04-beads-A|Size: 4x 500 µL

Acetyl-Lysine Antibody Mouse Monoclonal (19C4B2-1)

Acetyl-Lysine Antibody Mouse Monoclonal (19C4B2-1)

SKU: AAC03-S|Size: 1x 25 µL

Acetyl-Lysine Antibody Mouse Monoclonal (7B5A1)

Acetyl-Lysine Antibody Mouse Monoclonal (7B5A1)

SKU: AAC02-S|Size: 1x 25 µL

Acetyl-Lysine Control Beads

Acetyl-Lysine Control Beads

SKU: CIG02-beads-10|Size: 10 Assays

Acetyl-Lysine-HRP Antibody Mouse Monoclonal (19C4B2-1)

Acetyl-Lysine-HRP Antibody Mouse Monoclonal (19C4B2-1)

SKU: AAC03-HRP|Size: 1x 100 µL

Acetylated Tubulin protein Source - Porcine Brain

Acetylated Tubulin protein Source - Porcine Brain

SKU: CS-TAC01|Size: 1x 500 µg

Acti-stain 488 phalloidin

Acti-stain 488 phalloidin

SKU: PHDG1-A|Size: 1x 500 µL (300 slides)

Acti-stain 555 phalloidin

Acti-stain 555 phalloidin

SKU: PHDH1-A|Size: 1x 500 µL (300 slides)

Acti-stain 670 phalloidin

Acti-stain 670 phalloidin

SKU: PHDN1-A|Size: 1x 500 µL (300 slides)

Actin - HiLyte™ Fluor 488 Labeled (Rabbit skeletal muscle - >99% pure)

Actin - HiLyte™ Fluor 488 Labeled (Rabbit skeletal muscle - >99% pure)

SKU: AR06-B|Size: 10x 20 µg

Actin - HiLyte™ Fluor 555 Labeled (Rabbit skeletal muscle - >99% pure)

Actin - HiLyte™ Fluor 555 Labeled (Rabbit skeletal muscle - >99% pure)

SKU: AR07-C|Size: 20x 20 µg

Actin Binding Protein Spin-Down Assay Biochem Kit - human platelet actin

Actin Binding Protein Spin-Down Assay Biochem Kit - human platelet actin

SKU: BK013|Size: 30 - 100 Assays/Kit

Actin Binding Protein Spin-Down Assay Biochem Kit - rabbit skeletal muscle actin

Actin Binding Protein Spin-Down Assay Biochem Kit - rabbit skeletal muscle actin

SKU: BK001|Size: 30 - 100 Assays/Kit

Actin Polymerization Biochem Kit (fluorescence format) - rabbit skeletal muscle actin

Actin Polymerization Biochem Kit (fluorescence format) - rabbit skeletal muscle actin

SKU: BK003|Size: 30 - 100 Assays/Kit

Actin Protein (MICAL-Oxidized) : Rabbit Skeletal Muscle (Rabbit Muscle, > 95% Pure)

Actin Protein (MICAL-Oxidized) : Rabbit Skeletal Muscle (Rabbit Muscle, > 95% Pure)

SKU: MXA95|Size: 2x 250 µg

Actin polymerization buffer - 10x stock

Actin polymerization buffer - 10x stock

SKU: BSA02-001|Size: 1x 2 mL

Actin protein (>95% pure) - rabbit skeletal muscle

Actin protein (>95% pure) - rabbit skeletal muscle

SKU: AKL95-XL|Size: Large Quantities

Actin protein (>99% pure - human platelet beta gamma actin)

Actin protein (>99% pure - human platelet beta gamma actin)

SKU: APHL99-C|Size: 1x 1 mg

Actin protein (>99% pure) - bovine cardiac muscle

Actin protein (>99% pure) - bovine cardiac muscle

SKU: AD99-A|Size: 1x 1 mg

Actin protein (>99% pure) - chicken gizzard muscle

Actin protein (>99% pure) - chicken gizzard muscle

SKU: AS99-A|Size: 1x 1 mg

Actin protein (>99% pure) - rabbit skeletal muscle

Actin protein (>99% pure) - rabbit skeletal muscle

SKU: AKL99-E|Size: 20x 1 mg

Actin protein (biotin) - skeletal muscle

Actin protein (biotin) - skeletal muscle

SKU: AB07-C|Size: 20x 20 µg

Actin protein (pre-formed filaments) - rabbit skeletal muscle

Actin protein (pre-formed filaments) - rabbit skeletal muscle

SKU: AKF99-A|Size: 1x 1 mg

Actin protein (pyrene labeled) - rabbit skeletal muscle

Actin protein (pyrene labeled) - rabbit skeletal muscle

SKU: AP05-B|Size: 5x 1 mg

Actin protein (rhodamine labeled - beta gamma human platelet actin)

Actin protein (rhodamine labeled - beta gamma human platelet actin)

SKU: APHR-C|Size: 20x 10 µg

Actin protein (rhodamine) - rabbit skeletal muscle

Actin protein (rhodamine) - rabbit skeletal muscle

SKU: AR05-B|Size: 10x 20 µg

Alpha Tubulin N-Acetyltransferase 1 (2-236) protein (Human recombinant)

Alpha Tubulin N-Acetyltransferase 1 (2-236) protein (Human recombinant)

SKU: CS-TAT01|Size: 1x 100 µg

Alpha-actinin protein - rabbit skeletal muscle

Alpha-actinin protein - rabbit skeletal muscle

SKU: AT01-A|Size: 2x 50 µg

Anti-Acetyl Lysine Mouse Monoclonal Antibody Agarose Conjugates MAb clone 19C4B2.1

Anti-Acetyl Lysine Mouse Monoclonal Antibody Agarose Conjugates MAb clone 19C4B2.1

SKU: AAC03-beads|Size: 4x 500 µL

Anti-Acetyl Lysine Mouse Monoclonal Antibody Agarose Conjugates MAb clones 19C4B2.1 and 7B5A1

Anti-Acetyl Lysine Mouse Monoclonal Antibody Agarose Conjugates MAb clones 19C4B2.1 and 7B5A1

SKU: AAC04-beads|Size: 4x 500 µL

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 19C4B2.1

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 19C4B2.1

SKU: AAC03|Size: 2x 100 µL

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 3C6.08.20

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 3C6.08.20

SKU: AAC01|Size: 2x 100 µL

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 7B5A1

Anti-Acetyl Lysine Mouse Monoclonal Antibody MAb clone 7B5A1

SKU: AAC02|Size: 2x 100 µL

Anti-Cdc42 - Mouse Mab

Anti-Cdc42 - Mouse Mab

SKU: ACD04-S|Size: 1x 125 µL

Anti-Cdc42 Mouse Monoclonal Antibody

Anti-Cdc42 Mouse Monoclonal Antibody

SKU: ACD04|Size: 1x 500 µL

Anti-Pan Actin Mouse Monoclonal Antibody (Clone 7A8-2-1)

Anti-Pan Actin Mouse Monoclonal Antibody (Clone 7A8-2-1)

SKU: AAN02-S|Size: 1x 125 µL

Anti-Pan Actin Mouse Monoclonal Antibody (Clone 7A8.2.1)

Anti-Pan Actin Mouse Monoclonal Antibody (Clone 7A8.2.1)

SKU: AAN02|Size: 1x 500 µL

Anti-Phosphotyrosine Affinity Beads

Anti-Phosphotyrosine Affinity Beads

SKU: APY03-Beads|Size: 4x 330 µL

Anti-Phosphotyrosine Mouse Monoclonal Antibody

Anti-Phosphotyrosine Mouse Monoclonal Antibody

SKU: APY03|Size: 3x 100 µL

Anti-Phosphotyrosine-HRP Mouse Monoclonal Antibody

Anti-Phosphotyrosine-HRP Mouse Monoclonal Antibody

SKU: APY03-HRP|Size: 1x 100 µL

Anti-Rac1 - mouse Mab

Anti-Rac1 - mouse Mab

SKU: ARC03-S|Size: 1x 25 µL

Anti-Rac1 specific mouse MAb

Anti-Rac1 specific mouse MAb

SKU: ARC03|Size: 2x 100 µL

Anti-SUMO-1 Mouse Monoclonal Antibody

Anti-SUMO-1 Mouse Monoclonal Antibody

SKU: ASM01|Size: 1x 100 µL

Anti-SUMO-2/3 Mouse Monoclonal Antibody

Anti-SUMO-2/3 Mouse Monoclonal Antibody

SKU: ASM24|Size: 2x 200 µL

Anti-Ubiquitin Mouse Monoclonal Antibody

Anti-Ubiquitin Mouse Monoclonal Antibody

SKU: AUB01|Size: 2x 100 µL

Anti-Ubiquitin-HRP Antibody

Anti-Ubiquitin-HRP Antibody

SKU: AUB01-HRP|Size: 1x 100 µL

Anti-alpha/beta tubulin - sheep polyclonal

Anti-alpha/beta tubulin - sheep polyclonal

SKU: ATN02-S|Size: 1x 25 µL

Anti-profilin: rabbit polyclonal

Anti-profilin: rabbit polyclonal

SKU: APUF01-A|Size: 50 µg

Anti-tubulin polyAb pan specific (sheep)

Anti-tubulin polyAb pan specific (sheep)

SKU: ATN02|Size: 2x 100 µL

Arf1 Pull-down Activation Assay Biochem Kit (bead pull-down format) - 20 Assays

Arf1 Pull-down Activation Assay Biochem Kit (bead pull-down format) - 20 Assays

SKU: BK032-S|Size: 20 Assays/Kit

Arf6 Pull-down Activation Assay Biochem Kit (bead pull-down format) - 20 Assays

Arf6 Pull-down Activation Assay Biochem Kit (bead pull-down format) - 20 Assays

SKU: BK033-S|Size: 20 Assays/Kit

Arp2/3 protein complex - porcine brain

Arp2/3 protein complex - porcine brain

SKU: RP01P-A|Size: 2x 50 µg

BimC Motor Domain (Aspergillus nidulans)

BimC Motor Domain (Aspergillus nidulans)

SKU: BM01-A|Size: 2x 25 µg

BlastR Lysis/Dilution Buffer Kit

BlastR Lysis/Dilution Buffer Kit

SKU: BLR03-50|Size: 50 Lyses

BlastR Lysis/Dilution Kit

BlastR Lysis/Dilution Kit

SKU: BLR03|Size: 50 Lyses

BlastR Rapid Filtration Kit

BlastR Rapid Filtration Kit

SKU: BLR02|Size: 50 Purifications

BlastR Rapid Lysate Prep Kit

BlastR Rapid Lysate Prep Kit

SKU: BLR01|Size: 50 Purifications

CENP-E kinesin motor domain protein (KIF10) - GST tagged - Homo sapiens recombinant

CENP-E kinesin motor domain protein (KIF10) - GST tagged - Homo sapiens recombinant

SKU: CP01-A|Size: 2x 25 µg

Caki-1 tumor tubulin

Caki-1 tumor tubulin

SKU: CS-TM001|Size: 1x 250 µg

Cardiac Thin Filament Complex (CTFC)

Cardiac Thin Filament Complex (CTFC)

SKU: TFC01|Size: 1x 1 mg

Cdc42 G-LISA Activation Assay Kit (colorimetric)

Cdc42 G-LISA Activation Assay Kit (colorimetric)

SKU: BK127|Size: 96 Assays

Cdc42 G-LISA GTPase Activation Assay (Colorimetric format)

Cdc42 G-LISA GTPase Activation Assay (Colorimetric format)

SKU: BK127-S|Size: 24 Assays/Kit

Cdc42 Pull-down Activation Assay Biochem Kit (bead pull-down format)

Cdc42 Pull-down Activation Assay Biochem Kit (bead pull-down format)

SKU: BK034-S|Size: 20 Assays/Kit

Cdc42 Pulldown Activation Assay Kit

Cdc42 Pulldown Activation Assay Kit

SKU: BK034|Size: 50 Assays/Kit

Cdc42 protein - GST tagged - human dominant negative

Cdc42 protein - GST tagged - human dominant negative

SKU: C17G01-A|Size: 1x 25 µg

Cdc42 protein - GST tagged - human wild type

Cdc42 protein - GST tagged - human wild type

SKU: CDG01-XL|Size: 1x 1 mg

Cdc42 protein - His tagged - human constitutively active

Cdc42 protein - His tagged - human constitutively active

SKU: C6101-A|Size: 1x 10 µg

Cdc42 protein - His tagged - human wild type

Cdc42 protein - His tagged - human wild type

SKU: CD01-C|Size: 3x 100 µg

Chemically Acetylated Bovine Serum Albumin (BSA)

Chemically Acetylated Bovine Serum Albumin (BSA)

SKU: AACX1|Size: 2x 500 µg

Chromokinesin kinesin motor domain protein (KIF4) - GST tagged - Homo sapiens recombinant

Chromokinesin kinesin motor domain protein (KIF4) - GST tagged - Homo sapiens recombinant

SKU: CR01-A|Size: 2x 25 µg

Cofilin 1 protein - human recombinant

Cofilin 1 protein - human recombinant

SKU: CF01-XL|Size: 1x 1 mg

Control for Acetylation Immunoprecipitation IgG beads

Control for Acetylation Immunoprecipitation IgG beads

SKU: CIG02-beads|Size: 10 Assays

Control for Immunoprecipitation IgG beads

Control for Immunoprecipitation IgG beads

SKU: CIG01-beads|Size: 10 Assays

Control for SUM01 Immunoprecipitation IgG beads

Control for SUM01 Immunoprecipitation IgG beads

SKU: CIG03-beads|Size: 10 Assays

Control for Ubiquitin Affinity Beads

Control for Ubiquitin Affinity Beads

SKU: CUB02B-beads|Size: 10 Assays

CytoPhos Endpoint Phosphate Assay (BK054)

CytoPhos Endpoint Phosphate Assay (BK054)

SKU: BK054|Size: 1000 Assays/Kit

Cytoplasmic Dynein Motor Protein

Cytoplasmic Dynein Motor Protein

SKU: CS-DN01|Size: 50 µg

Dbs protein GEF domain - His tagged - human recombinant

Dbs protein GEF domain - His tagged - human recombinant

SKU: GE01-A|Size: 2x 50 µg

EFM Plasma membrane probe SP-468

EFM Plasma membrane probe SP-468

SKU: MG15-10|Size: 10 nmole

EFM Plasma membrane probe SQ-535

EFM Plasma membrane probe SQ-535

SKU: MG16-10|Size: 10 nmole

Eg5 Homolog Motor Domain (Asp-fum-)

Eg5 Homolog Motor Domain (Asp-fum-)

SKU: EG02-A|Size: 2x 15 µg

Eg5 kinesin motor domain protein (KIF11) - GST tagged - Homo sapiens recombinant

Eg5 kinesin motor domain protein (KIF11) - GST tagged - Homo sapiens recombinant

SKU: EG01-XL|Size: 1x 1 mg

Exoenzyme C3 transferase protein - His tagged -Clostridium botulinum recombinant

Exoenzyme C3 transferase protein - His tagged -Clostridium botulinum recombinant

SKU: CT03-A|Size: 1x 25 µg

F-actin Visualization Biochem Kit (fluorescence format)

F-actin Visualization Biochem Kit (fluorescence format)

SKU: BK005|Size: 300 Slides/Kit

Fascin-1 Protein - wild-type (Human recombinant)

Fascin-1 Protein - wild-type (Human recombinant)

SKU: CS-FSC01-B|Size: 1x 1 mg

Fibronectin (Biotinylated)

Fibronectin (Biotinylated)

SKU: FNR03-B|Size: 20x 20 µg

Fibronectin (Far-red HiLyte Fluor™ 647)

Fibronectin (Far-red HiLyte Fluor™ 647)

SKU: FNR04-A|Size: 5x 20 µg

Fibronectin (Fluorescent Red/Orange HiLyte Fluor™ 555 Labeled)

Fibronectin (Fluorescent Red/Orange HiLyte Fluor™ 555 Labeled)

SKU: FNR05-B|Size: 20x 20 µg

Fibronectin (Green fluorescent - HiLyte 488)

Fibronectin (Green fluorescent - HiLyte 488)

SKU: FNR02-B|Size: 20x 20 µg

FtsZ protein - E- coli recombinant 6xHis-tagged

FtsZ protein - E- coli recombinant 6xHis-tagged

SKU: FTZ05-B|Size: 5x 1 mg

FtsZ protein - E- faecalis recombinant 6xHis-tagged

FtsZ protein - E- faecalis recombinant 6xHis-tagged

SKU: FTZ04-B|Size: 5x 1 mg

FtsZ protein - S- aureus recombinant 6xHis-tagged

FtsZ protein - S- aureus recombinant 6xHis-tagged

SKU: FTZ02-XL|Size: Large Quantities

FtsZ protein - S- pneumoniae recombinant 6xHis-tagged

FtsZ protein - S- pneumoniae recombinant 6xHis-tagged

SKU: FTZ03-A|Size: 1x 1 mg

G-Actin/F-actin In Vivo Assay Biochem Kit

G-Actin/F-actin In Vivo Assay Biochem Kit

SKU: BK037|Size: 30 - 100 Assays/Kit

Actin

Resources & Documents
Cytoskeleton 2026 Campaign 5 - Actin Proteins and Kits

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Summary Sheet Campaign

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livecellprobes.pdf

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Activation Assay Brochure Final Web.pdf

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Actin Brochure v1.8 - web version.pdf

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Tubulin Brochure Final for Web.pdf

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small g-protein Brochure v3.5- final Web Version.pdf

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signal-seeker-ac-brochure-web.pdf

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