Eukaryotic Growth Factor Receptor Bound Protein 2 (Grb2)
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Catalog number
EPC514Hu61
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Price
Please ask
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Size
10ug
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Source
Eukaryotic expression
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Predicted Molecular Mass KD
26.8kDa
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Accurate Molecular Mass KD
27kDa
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Organism species
Homo sapiens (Human)
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Item Name
Growth Factor Receptor Bound Protein 2
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Alternative Names
ASH; NCKAP2; EGFRBP-GRB2; Grb3-3; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2
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Research Area
Signal transduction;
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Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
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Traits
Freeze-dried powder
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Isoelectric Point
5.9
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Purity
> 95%
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Protein length
Met1~Val217
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Tag
N-terminal His Tag
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Expression System
Eukaryotic expression
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Application
Positive Control; Immunogen; SDS-PAGE; WB.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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