Cellarcus Biosciences

Cellarcus Biosciences is a biotechnology company specializing in the analysis of extracellular vesicles (EVs), including exosomes, microvesicles, and apoptosomes. Founded in 2017 and based in La Jolla, California, Cellarcus is recognized for developing the vFC™ (vesicle flow cytometry) assay, a patented technology that enables standardized, single-vesicle analysis of EVs .

Core Technologies and Products

vFC™ Assay: A flow cytometry-based assay designed for the enumeration, sizing, and cargo analysis of individual EVs. It utilizes a membrane-selective dye and optimized antibodies to provide quantitative measurements with high sensitivity and specificity .

vTAG™ Antibodies: A suite of fluorescently labeled antibodies targeting common EV surface markers such as CD9, CD63, CD81, CD104, CD105, and phosphatidylserine. These antibodies are optimized for use with the vFC™ assay to enable multiplexed cargo analysis .

vCal™ Standards: Calibration standards, including nanoRainbow beads and Lipo100™ vesicle size standards, used to calibrate flow cytometers and ensure consistent and reproducible EV measurements .

Reference EV Samples: Characterized EVs derived from human platelets and red blood cells, available as reference materials for assay validation and inter-laboratory comparisons .

Services

evCRO Services: Cellarcus offers contract research organization (CRO) services for EV analysis, including assay design, sample analysis, and data interpretation. Their laboratory is equipped with specialized instrumentation and staffed by experts in EV research .