TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant
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Catalog number7254-1000
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Price:
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Size1 mg
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SynonymsECAT8
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Alternative_namesECAT8
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DescriptionInvolved in RISC complex and interaction with AEG-1 oncogene
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Molecular Weight13 kDa
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Storage Temp-80°C
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ShippingDry Ice
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Shelf Life12 months
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Concentration2 mg/ml
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AppearanceLiquid
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Physical form descriptionrh-TDRD12-BD2 is supplied as a solution in PBS Buffer containing 10% glycerol
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Background InformationTudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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Conjugationhistidine
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTDRD12
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Short nameTDRD12-BD2 (908-999 aa) (His-Tagged), recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Labelhis-tagged
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SpeciesHuman, Humans
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Alternative nameTDRD12-BD2 (908-999 aa) (histidine-Tagged), H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nametudor domain containing 12
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tudor domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data