JE (MCP-1), murine recombinant

  • Catalog number
    4207-1000
  • Supplier
  • Price
    4309.85 USD
  • Size
    1 mg
  • Synonyms
    Small inducible cytokine A2, CCL2, Monocyte chemotactic protein 1, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte secretory protein JE, HC11, chemokine (C-C motif) ligand 2, MCP1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434, GDCF-2 HC11, Immediate-early serum-responsive JE protein.
  • Alternative_names
    Small inducible cytokine A2, CCL2, Monocyte chemotactic protein 1, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte secretory protein JE, HC11, chemokine (C-C motif) ligand 2, MCP1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434, GDCF-2 HC11, Immediate-early serum-responsive JE protein.
  • Description
    Chemoattractant for monocytes and basophils
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥98%
  • Assay
    SDS-PAGE
  • Purity
    ≥98%
  • Biological activity
    Determined by measuring the dose dependent chemotaxis with human THP-1 cells. The ED₅₀ is in the range of 1-10 ng/ml
  • Results
    1-10 ng/ml
  • Molecular Weight
    13.8 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Sterile filtered and lyophilized with no additives
  • Reconstitution Instructions
    Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
  • Background Information
    Murine JE (also known as Macrophage/Monocyte Chemotactic Protein) is a 13.8 kDa protein containing 125 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    CCL2, CAPG, CCL13, CCL8, SLC25A33, CD46, CCR2, CCL7, IGHVII-1-1, MIR1-1
  • Short name
    JE (MCP-1), murine recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    JE (MCP-1), murine Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    C-C motif chemokine ligand 8
  • Synonyms gene
  • Synonyms gene name
    • small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
    • chemokine (C-C motif) ligand 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1996-11-14
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Chemokine ligands
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    CD46 molecule
  • Synonyms gene
  • Synonyms gene name
    • antigen identified by monoclonal antibody TRA-2-10
    • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
    • CD46 antigen, complement regulatory protein
    • CD46 molecule, complement regulatory protein
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1988-08-31
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Sushi domain containing
    • Complement system regulators and receptors
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (II)-1-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-1-1
    • immunoglobulin heavy variable (II)-1-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note:The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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