Fingolimod (FTY-720A, FTY720)

  • Catalog number
    1618-5
  • Price
    272.25 USD
  • Size
    5 mg
  • Alternative_name
    FTY-720A, FTY721
  • Description
    FTY720 can be phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). IC₅₀ of (S)- and (R)- FTY720-phosphate on lymphocyte migration toward 10 nM of S1P are 0.137 nM and 10.98 nM respectively. The IC₅₀ values to cell lines MCF-7 is 6.8±0.6 µM.
  • CAS Number
    162359-56-0
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₉H₃₃NO₂.HCl
  • Molecular Weight
    343.93
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (100 mg/ml) of EtOH (100 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A novel immune modulator
  • Storage Condition
    -20°C
  • Shipping Condition
    RT
  • Shelf Life
    24months
  • MDL Number
    MFCD00939512
  • PubChem CID
    107969
  • SMILES
    CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl
  • InChi
    InChI=1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H
  • InChi Key
    SWZTYAVBMYWFGS-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Fingolimod (FTY-720A, FTY720)
  • Alternative name
    Fingolimod (FTY-720A, FTY720)
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