- Catalog number1030-1
- Product nameEZAct™ Procathepsin Activation Buffer
- Size1 ml
- PriceAsk For Price
- DescriptionA ready-to-use buffer for generation of active Cathepsins by auto-activation of the Procathepsins.. Cathepsins (CTS) are proteases that degrade proteins. They are present in all animals and other organisms. These proteases are of three types: cysteine proteases, aspartyl protease and serine proteases. Cathepsins are produced as inactive proenzyme precursors that are subsequently activated in lysosomes. EZAct™ Procathepsin Activation Buffer is a ready-to-use buffer for generation of active cysteine/aspartyl Cathepsins by auto-activation of the Procathepsins.
- Product HighlightsAPPLICATIONS: 1. To generate active Cathepsins from inactive Procathepsins. 2. To test the activity of Cathepsins. 3. To screen for Cathepsin Inhibitor candidates. ACTIVATION PROTOCOL: 1. Adjust the concentration of the target Procathepsin to 0.5-5 mg/ml with the appropriate buffer. 2. Add equal amounts of EZAct™ Procathepsin Activation Buffer and mix well by pipetting up and down. 3. Incubate at the appropriate temperature (4°/ 22°/ 37°C) for the study. 4. Check the cathepsin activation by testing with an appropriate substrate. Note: BioVision’s Cathepsin Assay kits can be used for assaying the Cathepsin activity. Choose from assay kits: K140, K141, K142, K143, K144, K145 and K146.
- Storage Temp-20°C
- Shippinggel pack
- Shelf Life12 months
- Datasheet
- NotesFor research use only. Not to be used for human or animal treatment or consumption.
- Gene targetEZAct™ Procathepsin Activation
- Short nameEZAct™ Procathepsin Activation
- technique filter
- activation
- Techniqueactivation