- Catalog number7681-20
- Product nameExodus-2, Mouse Recombinant
- Size20 ug
- PriceAsk For Price
- SynonymsC-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21
- Alternative namesC-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21
- DescriptionA chemokine which inhibits hemopoiesis and stimulates chemotaxis
- RecombinantYes
- SourceE. coli
- Purity by SDS PAGE≥98%
- AssaySDS-PAGE
- Endotoxin Level≤ 1 EU/ug protein
- Biological activityThe activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
- Results200 ng/mL- 600 ng/mL.
- Molecular Weight12 kDa
- Storage Temp-20°C
- Shippinggel pack
- Shelf Life12 months
- AppearanceLyophilized powder
- Physical form descriptionLyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
- Reconstitution InstructionsRecommended reconstitution in sterile water at a concentration of 0.1 mg/mL
- Background InformationExodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
- Amino acid sequenceSDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
- HandlingCentrifuge the vial prior to opening.
- UsageFor Research Use Only! Not to be used in humans
- Datasheet
- Gene targetExodus-2
- Identity:HGNC:10620
- Gene:CCL21
- Long gene name:C-C motif chemokine ligand 21
- Synonyms gene name:small inducible cytokine subfamily A (Cys-Cys), member 21, chemokine (C-C motif) ligand 21
- Synonyms:SLC, exodus-2TCA4CKb96CkineECL
- Discovery year:1997-04-10
- Entrez gene record:6366
- Pubmed identification:9235955
- RefSeq identity:NM_002989
- Classification:Chemokine ligands
- VEGA ID:OTTHUMG00000019838
- Gene symbolCCL21
- Hostmouse
- Short nameExodus-2, Mouse Recombinant
- technique filter
- Recombinant
- Mouse
- TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
- Alternative techniquerec, murine