Recombinant Stem Cell Factor Receptor (SCFR)
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Catalog numberRPU43891
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Price:
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Size10 μg
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Verified reactivityMus musculus (Mouse)
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Protein numberP05532
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Gene namePlease refer to GenBank
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Other nameCD117; KIT; C-Kit; PBT; p145 c-Kit; C-Kit Receptor; Tyrosine-Protein Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Piebald Trait
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Protein originE.coli
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Protein regionPlease contact us.
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Protein sequencePlease contact us.
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Information about sequenceTyr343~Pro527
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Expected molecular weight22,2kDa
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Protein purity≥ 95%
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Verified applicationsSDS-PAGE; WB; ELISA; IP.
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Storage recommendationAliquot and store at -20°C. Minimize freezing and thawing.
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Use before1 year
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Shipping requirementsBlue ice
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Estimated production time7-11 business days
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NotesFor research use only. Not for diagnostic procedures.
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DescriptionFor cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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TestStem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.
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Gene target
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Gene symbolKIT
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Short nameRecombinant Stem Factor Receptor (SCFR)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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LabelN-terminal His-Tag
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Alternative nameRec. progenitor cellular Factor Receptor (SCFR)
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Alternative techniquerec
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Tissuecell, stem
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Gene info
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Identity
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Gene
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Long gene nameKIT proto-oncogene, receptor tyrosine kinase
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Synonyms gene
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Synonyms gene name
- piebald trait
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor tyrosine kinases
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data