Recombinant Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
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Catalog numberRPU43562
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Price:
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Size500 μg
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Verified reactivityHomo sapiens (Human)
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Protein numberO14788
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Gene numberPlease refer to GenBank
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Other nameCD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
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Protein originE.coli
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Protein regionPlease contact us.
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Protein sequencePlease contact us.
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Information about sequenceIle79~Ile247
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Expected molecular weight23.1kDa
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Protein purity≥ 98%
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Verified applicationsSDS-PAGE; WB; ELISA; IP.
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Storage recommendationAliquot and store at -20°C. Minimize freezing and thawing.
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Use before1 year
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Shipping requirementsBlue ice
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Estimated production time7-11 business days
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NotesFor research use only. Not for diagnostic procedures.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Short nameRecombinant Receptor Activator Of Factor Kappa B Ligand (RANkL)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Labeltwo N-terminal Tags, His-tag and T7-tag
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Alternative nameRec. Receptor Activator on Nuclear Factor Kappa B Ligand (RANkL)
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Alternative techniquerec
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MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data