Sphingosine 1 Phosphate Receptor 1 (EDG-1) - Membrane Preparation

• Catalog number
  X1273MP
• Price
  Please ask
• Size
  50 Tests

• Category
  Other Reagents
• Long description
  EDG1 (S1P1) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG1 (S1P1) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG1 (S1P1) is expressed in cardiovascular, leukocyte- containing and other tissues.
• Antibody come from
  n/a
• Other description
  No other information available
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Sphingosine 1 Phosphate Receptor 1 (EDG-1) - Membrane Preparation
• Antibody is raised in
  see techfile
• Antibody s reacts with
  N/A
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  [35S]GTPgS Labeling
• Antibody s suited for
  Optimal concentration should be evaluated by serial dilutions.
• Storage
  -80ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Sphingosine   Phosphate   Receptor   EDG-1   Membrane   Preparation  
• Gene symbol
  S1PR1, HEXIM1, S1PR5, LPAR2, LPAR1, BUD31, S1PR3, LPAR3, IGHVII-1-1, MIR1-1
• Short name
  Sphingosine 1 Phosphate Receptor 1 (EDG-1) - Preparation
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  Sphingosine 1 Phosphate Receptor 1 (EDG-1) - Membrane Preparation

Gene info

• Identity
  HGNC:3165
• Gene
  S1PR1
• Long gene name
  sphingosine-1-phosphate receptor 1
• Synonyms gene
  • EDG1
• Synonyms gene name
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
• Synonyms
  • edg-1
  • D1S3362
  • CD363
• GenBank acession
  • M31210
• Locus
  1p21.2
• Discovery year
  1998-05-15
• Entrez gene record
  1901
• Pubmed identfication
  • 2160972
  • 9488656
• RefSeq identity
  • NM_001400
• Classification
  • CD molecules
  • Sphingosine 1-phosphate receptors
• VEGA ID
  OTTHUMG00000010835

Gene info

• Identity
  HGNC:24953
• Gene
  HEXIM1
• Long gene name
  HEXIM P-TEFb complex subunit 1
• Synonyms gene name
  • hexamethylene bisacetamide inducible 1
• Synonyms
  • CLP-1
  • HIS1
  • MAQ1
  • EDG1
• GenBank acession
  • AB021179
• Locus
  17q21.31
• Discovery year
  2005-06-27
• Entrez gene record
  10614
• Pubmed identfication
  • 12119119
  • 12832472
• RefSeq identity
  • NM_006460
• Classification
  • P-TEFb complex subunits
• VEGA ID
  OTTHUMG00000180112

Gene info

• Identity
  HGNC:14299
• Gene
  S1PR5
• Long gene name
  sphingosine-1-phosphate receptor 5
• Synonyms gene
  • EDG8
• Synonyms gene name
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
• Synonyms
  • Edg-8
• GenBank acession
  • AK074661
• Locus
  19p13.2
• Discovery year
  2001-01-02
• Entrez gene record
  53637
• Pubmed identfication
  • 10799507
• RefSeq identity
  • NM_030760
• Classification
  • Sphingosine 1-phosphate receptors
• VEGA ID
  OTTHUMG00000180581

Gene info

• Identity
  HGNC:3168
• Gene
  LPAR2
• Long gene name
  lysophosphatidic acid receptor 2
• Synonyms gene
  • EDG4
• Synonyms gene name
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
• Synonyms
  • EDG-4
  • LPA2
• GenBank acession
  • AF011466
• Locus
  19p13.11
• Discovery year
  1999-02-15
• Entrez gene record
  9170
• Pubmed identfication
  • 9525886
  • 9804623
• RefSeq identity
  • NM_004720
• Classification
  • Lysophosphatidic acid receptors
• VEGA ID
  OTTHUMG00000182328

Gene info

• Identity
  HGNC:3166
• Gene
  LPAR1
• Long gene name
  lysophosphatidic acid receptor 1
• Synonyms gene
  • EDG2
• Synonyms gene name
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
• Synonyms
  • edg-2
  • rec.1.3
  • vzg-1
  • Gpcr26
  • Mrec1.3
  • LPA1
• GenBank acession
  • U80811
• Locus
  9q31.3
• Discovery year
  1998-05-15
• Entrez gene record
  1902
• Pubmed identfication
  • 8922387
  • 9070858
• RefSeq identity
  • NM_057159
• Classification
  • Lysophosphatidic acid receptors
• VEGA ID
  OTTHUMG00000020486

Gene info

• Identity
  HGNC:29629
• Gene
  BUD31
• Long gene name
  BUD31 homolog
• Synonyms gene
  • G10
• Synonyms gene name
  • G10 maternal transcript homolog (Xenopus laevis)
  • BUD31 homolog (yeast)
  • BUD31 homolog (S. cerevisiae)
• Synonyms
  • YCR063W
  • EDG-2
  • EDG2
  • fSAP17
  • Cwc14
• Synonyms name
  • functional spliceosome-associated protein 17
• GenBank acession
  • BC022821
• Locus
  7q22.1
• Discovery year
  2006-03-10
• Entrez gene record
  8896
• Pubmed identfication
  • 7841202
• RefSeq identity
  • NM_003910
• Classification
  • Spliceosomal C complex
  • NTC associated proteins
  • Spliceosomal B complex
  • Spliceosomal Bact complex
  • Spliceosomal P complex
• VEGA ID
  OTTHUMG00000154602

Gene info

• Identity
  HGNC:3167
• Gene
  S1PR3
• Long gene name
  sphingosine-1-phosphate receptor 3
• Synonyms gene
  • EDG3
  • C9orf47
  • C9orf108
• Synonyms gene name
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
  • chromosome 9 open reading frame 47
  • chromosome 9 open reading frame 108
• Synonyms
  • EDG-3
  • FLJ37523
  • bA791O21.3
• Synonyms name
  • sphingosine-1-phosphate receptor 3
• GenBank acession
  • AF022139
• Locus
  9q22.1
• Discovery year
  1998-05-15
• Entrez gene record
  1903
• Pubmed identfication
  • 8878560
  • 9409733
• RefSeq identity
  • NM_005226
• Classification
  • Sphingosine 1-phosphate receptors
• VEGA ID
  OTTHUMG00000020173

Gene info

• Identity
  HGNC:14298
• Gene
  LPAR3
• Long gene name
  lysophosphatidic acid receptor 3
• Synonyms gene
  • EDG7
• Synonyms gene name
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
• Synonyms
  • LP-A3
  • Edg-7
  • RP4-678I3
  • HOFNH30
  • LPA3
• GenBank acession
  • AF127138
• Locus
  1p22.3
• Discovery year
  2001-01-02
• Entrez gene record
  23566
• Pubmed identfication
  • 10488122
• RefSeq identity
  • NM_012152
• Classification
  • Lysophosphatidic acid receptors
• VEGA ID
  OTTHUMG00000009925

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

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